Volume 75March 2014Number 3

Review Article

205 Review of Maintenance Trials for Major Depressive Disorder: A 25-Year Perspective From the US Food and Drug Administration

Silvana Borges, Yeh-Fong Chen, Thomas P. Laughren, Robert Temple, Hiren D. Patel, Paul A. David, Mitchell Mathis, Ellis Unger, Peiling Yang, and Ni A. Khin

CME Background

CME Article

263 Posttest


254 A Prospective 4-Year Naturalistic Follow-Up of Treatment and Outcome of 300 Bipolar I and II Patients

Christian Simhandl, Barbara König, and Benedikt L. Amann


CME Commentary

275 Posttest


274 Schizophrenia: The Role of Dopamine and Glutamate [Free Access]

Anissa Abi-Dargham and Jonathan M. Meyer

Original Research

215 A Direct, Controlled, Blind Family Study of DSM-IV Pathological Gambling

Donald W. Black, William H. Coryell, Raymond R. Crowe, Brett McCormick, Martha C. Shaw, and Jeff Allen

222 Cost-Effectiveness of Prolonged Exposure Therapy Versus Pharmacotherapy and Treatment Choice in Posttraumatic Stress Disorder (the Optimizing PTSD Treatment Trial): A Doubly Randomized Preference Trial

Quang A. Le, Jason N. Doctor, Lori A. Zoellner, and Norah C. Feeny

231 Do Clinical Trials of Treatment of Alcohol Dependence Adequately Enroll Participants With Co-Occurring Independent Mood and Anxiety Disorders? An Analysis of Data From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

Nicolas Hoertel, Bruno Falissard, Keith Humphreys, Philip Gorwood, Anne-Sophie Seigneurie, and Frédéric Limosin

238 Weight Change and Metabolic Effects of Asenapine in Patients With Schizophrenia and Bipolar Disorder

David E. Kemp, Jun Zhao, Pilar Cazorla, Ronald P. Landbloom, Mary Mackle, Linda Snow-Adami, and Armin Szegedi

247 Trends in Office-Based Mental Health Care Provided by Psychiatrists and Primary Care Physicians

Mark Olfson, Kurt Kroenke, Shuai Wang, and Carlos Blanco

264 Memantine for Fragile X–Associated Tremor/Ataxia Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Andreea L. Seritan, Danh V. Nguyen, Yi Mu, Flora Tassone, James A. Bourgeois, Andrea Schneider, Jennifer B. Cogswell, Kylee R. Cook, Maureen A. Leehey, Jim Grigsby, John M. Olichney, Patrick E. Adams, Wendi Legg, Lin Zhang, Paul J. Hagerman, and Randi J. Hagerman

276 Latent Class Analysis of Personality Disorders in Adults With Posttraumatic Stress Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

Jack Tsai, Ilan Harpaz-Rotem, Corey E. Pilver, Erika J. Wolf, Rani A. Hoff, Kenneth N. Levy, Jitender Sareen, and Robert H. Pietrzak

ASCP Corner

285 The Endocannabinoid System and Schizophrenia: Links to the Underlying Pathophysiology and to Novel Treatment Approaches

Swapnil Gupta, John D. Cahill, Mohini Ranganathan, and Christoph U. Correll

Letters to the Editor

288 High-Dose Cholinergic Therapy With Rivastigmine Patch Does Not Prolong QTc Time in Patients With Alzheimer’s Disease

Matthias W. Riepe

289 The Problem of Patient Heterogeneity and Lack of Proper Training in a Study of EEG Neurofeedback in Children

Rex L. Cannon, H. E. Pigott, Tanju Surmeli, Deborah R. Simkin, Robert W. Thatcher, Werner Van den Bergh, Gerald Gluck, Joel F. Lubar, Richard Davis, Dale S. Foster, Jonathan Douglas, Atholl T. Malcolm, Donald Bars, Kirk Little, Wes Center, Marvin Berman, Harold Russell, Barbara Hammer, and J. Lucas Koberda

Reply by van Dongen-Boomsma and Colleagues

290 Correction [Free Access]

Weisler RH, Nolen WA, Neijber A, Hellqvist Å, Paulsson B, for the Trial 144 Study Investigators. Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study) (J Clin Psychiatry 2011;72[11]:1452–1464)

Online Exclusives

Practical Psychopharmacology

e198 Antidepressants and Testicular Cancer: Cause Versus Association

Original Research

e184 Completed and Attempted Suicides Among 18,154 Subjects With Schizophrenia Included in a Large Simple Trial [Free Access]

e191 Violent and Serious Suicide Attempters: One Step Closer to Suicide?

Book Review

e201 Cognitive-Behavior Therapy for Children and Adolescents

Online Activities

e05 Misdiagnosis of Bipolar Depression in Primary Care Practices [CME]

e06 Common Comorbidities and Differential Diagnosis of Restless Legs Syndrome [CME]

e07 Presentation and Treatment of Complicated Obsessive-Compulsive Disorder [CME]

Information for Authors

see www.psychiatrist.com/author.htm