Primary Care Companion J Clin Psychiatry 2000;2:107-110
© Copyright 2014 Physicians Postgraduate Press, Inc.
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The interictal “schizophrenia-like” psychoses of
epilepsy conventionally are treated with antipsychotic medication
with uncertain results. In patients with these psychoses, a
preceding and concomitant dysphoric disorder usually can be
documented. Effectiveness of the pharmacologic treatment by
the combination of drugs that is effective for severe interictal
dysphoric disorders is demonstrated in a series of patients with
interictal psychosis. Method: Patients were treated with the
combination of a tricyclic antidepressant and a selective serotonin
reuptake inhibitor, enhanced if necessary by a small amount
of the atypical neuroleptic risperidone.