Primary Care Companion J Clin Psychiatry 2001;3(6):270-274
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Roughly 65% of patients with acute myocardial infarction report experiencing depressive symptoms, and 15% to 22% of
these patients have major depressive disorder. However, only
25% of cardiac patients with major depression receive a diagnosis of the disorder, and only half of those patients receive
treatment. In otherwise healthy persons, depression is an independent risk factor in the development of and mortality associated with cardiovascular disease, and depressed individuals
with preexisting cardiovascular disease have a 3.5-fold greater
risk of death than nondepressed individuals with cardiovascular disease.