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Our Collaborative Veterans Initiative
John S. Shelton, PhD

Find out about a national effort designed to improve the quality of mental health care received by returning veterans.

» Read this post

» Read the entire blog

Assessment and Management of Bipolar I Depression Gary S. Sachs, MD

New! Discover how pre-assessment tools can create more time for you to engage with patients and make wiser treatment choices.

>>See the entire activity

Call for papers! Submit original research, review articles, case reports, brief reports, commentaries, rounds, and letters. Typical topics include depression, anxiety, dementia, MS, ADHD, and sleep disorders.

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Published Online 6-6-13

Educational Impact of a Psychiatric Liaison in the Medical Intensive Care Unit: Effects on Attitudes and Beliefs of Trainees and Nurses Regarding Delirium

[Abstract] [Full Text]

Published Online 5-30-13

Association Between Severity of Depression and Self-Perceived Cognitive Difficulties Among Full-Time Employees

[Abstract] [Full Text]

Published Online 5-9-13

Electrocardiographic Abnormalities as Potential Contributors to Premature Mortality in Patients With Mental Illness in a Psychiatric Day Treatment Program [Free Access]

[Abstract] [Full Text]

Published Online 5-2-13

Six-Month Open-Label Follow-Up of Risperidone Long-Acting Injection Use in Pediatric Bipolar Disorder

[Abstract] [Full Text]

Features & Letters

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Published Online 6-13-13

Psychotherapy Casebook: Arbitrary Inference

[Full Text]

Published Online 5-23-13

Letter to the Editor: Hirsutism in a Female Adolescent Induced by Long-Acting Injectable Risperidone: A Case Report

[Full Text]

Published Online 5-16-13

Rounds in the General Hospital: Intoxications Associated With Agitation, Tachycardia, Hypertension, and Fever: Differential Diagnosis, Evaluation, and Management

[Full Text]

Published Online 5-2-13

Letter to the Editor: A Case of Cocaine-Induced Myopathy

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Current Issue

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Volume 152013Number 2

Articles

Psychiatric Disorders and Quality of Life in Patients With Implantable Cardioverter Defibrillators: A Systematic Review

[Abstract] [Full Text] [Clinical Points] [Listen]

Clinical Points
  • Implantable cardioverter defibrillators, while potentially effective for the prevention of sudden death, may have serious psychological effects for patients and their families.
  • The frequency and intensity of shocks may promote anxiety and depression and may worsen depressive and anxiety disorders among those who already have them.
  • New strategies should be developed to improve quality of life and minimize psychiatric disorders that can be triggered with the implant of a cardioverter defibrillator or the first shock.

[Close]

A Review of Antidepressant Therapy in Primary Care: Current Practices and Future Directions [Free Access]

[Abstract] [Full Text] [Clinical Points] [Listen]

Clinical Points
  • Symptom presentation, level of severity, and response to antidepressants are equivalent between patients treated in primary care and specialty psychiatric clinics.
  • There should be some evidence of improvement of symptoms after 2 weeks; if not, then dose adjustment or other interventions should be considered to achieve virtual absence of all symptoms; evidence supporting add-on therapies is inconclusive, and they may increase side effects.
  • New research to find biomarkers of depression subtypes may help to select specific targets for new and existing antidepressants; the novel antidepressant vortioxetine may provide favorable outcomes as a monotherapy for a wider range of depressed patients.

[Close]

Depression and Chronic Diseases: It Is Time for a Synergistic Mental Health and Primary Care Approach

[Abstract] [Full Text] [Clinical Points] [Listen]

Clinical Points
  • The mean life span in depressed patients is 25 to 30 years shorter than that in the general population, and the impact of depression on public health is on par with that of smoking and obesity.
  • Depression can be reliably diagnosed and treated in the primary care setting.
  • There are evidence-based, simple, and cost-effective screening tools to identify depression.

[Close]

A Review of Butyrylcholinesterase as a Therapeutic Target in the Treatment of Alzheimer’s Disease

[Abstract] [Full Text] [Clinical Points] [Listen]

Clinical Points
  • Evidence for a role of butyrylcholinesterase (BuChE), including an effect of BuChE genotype, in the pathology of Alzheimer’s disease is increasing.
  • There are pharmacologic differences between the 3 main cholinesterase inhibitors approved for the symptomatic treatment of Alzheimer’s disease, which may affect the clinical response; rivastigmine inhibits both acetylcholinesterase (AChE) and BuChE, while donepezil and galantamine are AChE-selective.
  • An increased understanding of the relative importance of BuChE versus AChE over the disease course will help inform treatment decisions and optimize outcomes for each patient.

[Close]

Rounds From Banner Alzheimer's Institute

As Time Goes By [CME]

[Full Text] [Posttest] [Clinical Points] [Listen]

Clinical Points
  • To improve the quality of life of those with dementia and of their caregivers, clinicians need to treat the symptoms that can be managed, as well as comorbid depression and agitation, and provide caregivers with management strategies.
  • Medication management of behavioral manifestations of dementia is often beneficial.
  • Caregiver counseling and support is a vital part of treating behavioral manifestations of dementia.

[Close]

Rounds in the General Hospital

Using Stimulants for Attention-Deficit/Hyperactivity Disorder: Clinical Approaches and Challenges

[Full Text] [Clinical Points] [Listen]

Clinical Points
  • Attention-deficit/hyperactivity disorder (ADHD) is a common disorder of children, adolescents, and adults; moreover, it coexists with a bevy of other psychiatric and medical disorders. Pharmacotherapy of ADHD with stimulants is a mainstay of evidence-based treatment for ADHD across the lifespan.
  • Stimulants have relatively few serious interactions with commonly prescribed medications.
  • Certain adverse effects of stimulants (eg, decreased appetite, insomnia) can be anticipated by virtue of their known pharmacologic properties, whereas others (eg, tics, mood changes, sudden death) are idiosyncratic.

[Close]

Psychotherapy Casebook

Revisiting the Role of a Palliative Care Psychiatrist

[Full Text] [Listen]

Letters to the Editor

“K2/Spice”: Have You Updated Your Differentials? A Case Report

[Full Text]

Psychiatric Features in High-Functioning Adult Brothers With Fragile X Spectrum Disorders

[Full Text]

A Case of Amelioration of Venlafaxine-Discontinuation “Brain Shivers” With Atomoxetine

[Full Text]

Relationship Between Rages and Criminal Behavior in an Internal Medicine Outpatient Sample

[Full Text]

Are “Bath Salts” on Your Differential List? A Case Report of Delirium and Agitation After Use of Illicit Bath Salts

[Full Text]

Online Journal Offerings | NEW! Browse all articles in our Topic Collections.

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Special Sections

Delayed Cognitive Impairment After a Hypoxic Event

Roy Yaari, Helle Brand, James D. Seward, Anna D. Burke, Adam S. Fleisher, and Pierre N. Tariot

In this issue of the Companion, we highlight the case of a 43-year-old woman with impaired cognition who was evaluated on the inpatient psychiatric unit following a suicide attempt. Following discharge from the hospital, she began displaying bizarre behaviors and was eventually readmitted to the psychiatric unit. Does the patient have an underlying psychiatric disorder, substance abuse issues, or a brain lesion?

>>See the entire activity

>>See all available Rounds

The Cognitive Impact of Atrial Fibrillation

Anne F. Gross and Theodore A. Stern

Have you ever wondered if atrial fibrillation predisposes your patients to cognitive impairment, and, if it does, by what mechanisms? Read this review and discussion of the literature to learn about central nervous system complications that can develop in association with atrial fibrillation and to explore treatment options for this condition.

>>See the entire article

>>See all available Rounds

Residual Symptoms in Major Depressive Disorder: Prevalence, Effects, and Management

John Zajecka, Susan G. Kornstein, and Pierre Blier

Even after achieving response or remission, patients with MDD often have residual symptoms that negatively affect their functioning and quality of life. Here, find out about the neurochemical mechanisms involved in MDD, how to identify residual depressive symptoms, and formulate a long-term treatment plan so that you can target interventions to promote optimal outcomes for each patient.

>>See the entire activity

>>See all available
PCC Academic Highlights

Grieving the Loss of a Friend

Dean Schuyler

Interactions with a patient at the end of life can leave a deep impression on the caregiver. In this issue’s Psychotherapy Casebook, Dr Schuyler provides an account of his 4-month friendship with Mr A, a man with terminal cancer who was negotiating his final life stage. When Mr A finally died, he left an empty space in Dr Schuyler's life.

>>See the entire article

>>See all available Psychotherapy Casebook articles

CME

Five-Year Course of OCD

Jane L. Eisen, MD (Chair), et al

What types of primary obsessions are associated with a better or worse course of obsessive-compulsive disorder? Find out in this activity.

>>See the entire activity

>>See all Journal CME activities

Measurement-Based Assessment in Depression

Madhukar H. Trivedi, MD

Learn about using the PHQ-9, QIDS, BDI, and other tools to assess your patients, track their symptoms, and modify their treatment plans.

>>See the entire activity

>>See all Multimedia activities

How to Interpret Findings Concerning Newly Approved Antipsychotics

Christoph U. Correll, MD (Chair), et al

Review a compilation of a detailed panel discussion on the results of the PEARL 2 study. The goal is to help you better understand how to translate data from pivotal antipsychotic trials into useful information for managing specific patients.

>>See the entire activity

>>See all Special Features

Learn. Practice. Treat.

Perceptions, Expectations, and Management of Negative Symptoms

Stephen R. Marder, MD

Find out why clinicians often underestimate the presence and severity of negative symptoms and what you can do to better assess and manage them.

>>See the entire activity

>>See related activities

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