The article you requested is
Drug Craving and Other Negative Reactions After Abrupt Substitution of Nefazodone for Other Serotonergic Agents
J Clin Psychiatry 1996;57(10):486-487 [letter]
© Copyright 2015 Physicians Postgraduate Press, Inc.
Letter to the Editor
Sir: Nefazodone is a relatively new antidepressant medication with a novel profile of neurochemical effects: potent blockade of the 5-HT2A receptor, inhibition of the serotonin reuptake pump at higher concentrations, and transient norepinephrine reuptake inhibition. Among the potential consequences of this profile include antidepressant and anxiolytic efficacy and decreased incidence of medication-related complaints of insomnia and anxiety. Given its reputed lack of sexual side effects, nefazodone is now regarded as a particularly useful option in cases where these side effects interfere with patient satisfaction and compliance with treatment.