Reversible Parkinsonism in a 90-Year-Old Man Taking Sertraline

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Letter to the Editor

Sir: Since 1979, there have been reports of extrapyramidal effects, including dystonia, akathisia, and parkinsonism, associated with the use of serotonin selective reuptake inhibitors (SSRIs) in young, healthy patients. There are few reports of SSRI-related extrapyramidal effects in the elderly or neurologically impaired, although such individuals might be more vulnerable. French physicians reported deterioration of parkinsonian patients taking SSRIs.

J Clin Psychiatry 1997;58(6):275 [letter]