Introduction/Augmentation of Antidepressant Medication




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Eight new antidepressants have been introduced in the past decade (Table 1). The improved safety, tolerability, and perceived effectiveness of these medications have dramatically increased public awareness of depression as a serious illness and have contributed to the increase in acceptance of medication as a treatment modality. Despite advances in the diagnosis and treatment of depressive illness, the outcome of pharmacotherapy remains unsatisfactory for many patients.

J Clin Psychiatry 1998;59(suppl 5):5–12