SSRI-Induced Parkinsonism May Be an Early Sign of Future Parkinson's Disease

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Letter to the Editor

Sir: In recent years, there have been several case reports of extrapyramidal symptoms as a result of treatment with selective serotonin reuptake inhibitors (SSRIs). These symptoms include dystonia, akathisia, and parkinsonism. In most previously reported cases, the patients had preexisting brain diseases, but some movement disorders developed after initiation of SSRI treatment in both young healthy and vulnerable old patients.

J Clin Psychiatry 1999;60(6):410