Clinical and Demographic Features of Atypical Depression in Outpatients With Major Depressive Disorder: Preliminary Findings From STAR*D.[CME]
J Clin Psychiatry 2005;66(8):1002-1011
© Copyright 2017 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Objective: To determine the frequency and
demographic and clinical characteristics of depression with
atypical features in a broadly representative sample of
Method: Data derived from the first 1500
patients with DSM-IV major depressive disorder enrolled in the
Sequenced Treatment Alternatives to Relieve Depression trial at
41 primary care and nonresearch psychiatric outpatient clinics.
An algorithm based on the 30-item Inventory of Depressive
Symptomatology-Clinician Rating (IDS-C30) determined presence or
absence of depression with atypical features. Odds ratios
determined whether a variety of demographic and clinical
parameters differed between patients meeting and not meeting
Results: Over 18% of the sample met criteria for
atypical features based on items from the IDS-C30. The atypical
group was more likely to be female and have an earlier age at
onset, greater comorbidity with anxiety symptoms, and greater
symptom severity compared with the nonatypical group.
Conclusion: Previously identified features of
atypical depression were confirmed in this large and broadly
representative, nonresearch clinical population.