Validation of the Mood Disorder Questionnaire for Bipolar Disorders in Adolescents
J Clin Psychiatry 2006;67(5):827-830
© Copyright 2017 Physicians Postgraduate Press, Inc.
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Objective: The study was designed to
determine the validity of the Mood Disorder
Questionnaire - Adolescent Version (MDQ-A) as a
screening instrument for bipolar disorders (I, II,
not otherwise specified, and cyclothymia) in an
adolescent outpatient psychiatric population.
Method: 104 adolescents and their
parents completed the MDQ-A. Three versions of the MDQ-A were compared: (1) self report of
symptoms by adolescent, (2) attributional
report-how the adolescent believed teachers or friends
would report his/her symptoms, and (3) parent report
of adolescent's symptoms. DSM-IV diagnosis was made based upon the
clinician-administered Schedule for Affective Disorders and
Schizophrenia for School-Age Children-Present and
Lifetime Version (K-SADS-PL), a semistructured
diagnostic interview. MDQ-A items were summed,
yielding a score for each adolescent ranging from 0
to 13 on each of the 3 MDQ - A versions. Each possible scoring threshold, in combination with
co-occurrence of symptoms and behaviors and with moderate to serious problems caused by
symptoms, was crossed with the results of the K-SADS-PL diagnostic interview to assess
sensitivity and specificity. The study was conducted
from April 2002 to September 2003.
Results: A score of 5 or more items on
the parent version yielded a sensitivity of 0.72
and specificity of 0.81, which were superior to
self and attributional versions.
Conclusions: The MDQ-A completed by
parents about their adolescents' symptoms may be a useful screening instrument for bipolar
disorders in an adolescent psychiatric outpatient