Use of Antidepressants and Suicide Rate in Finland: An Ecological Study
J Clin Psychiatry 2007;68(4):505-511
© Copyright 2014 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Objective: The suicide rate has decreased in many countries, while the use of antidepressants has increased greatly. The aim of this study was to investigate the associations between use of antidepressants and suicide rate.
Method: Population-based suicide rates and reimbursed prescriptions of antidepressants between 1994 and 2001 in Finland were analyzed in the whole population, and separately by gender, age, and geographical region.
Results: There were significant differences in suicide rates between men and women (p < .0001), but there were no differences between different regions of the country. The decline in the suicide rate was significantly associated
with use of antidepressants among men aged 15 to 44 (p < .0001), 45 to 64 (p = .0005), and 75 years and over (p = .001) and men in 3 regions (p < .001). The decline in the suicide rate was significantly associated with the use of antidepressants among 15- to 44-year-old women (p = .008) and women in 1 region (p = .013). Use of antidepressants had a significant association with the decrease in the suicide rate (risk ratio = 0.08, 95% CI 0.02 to 0.30, p < .001), despite the effect of background variables, their interaction, and the course of time.
Conclusions: An increase in the use of antidepressants may decrease the suicide rate. Baseline suicide rate and access to health care may influence this association.