An Evidence-Based Medicine Strategy for Achieving Remission in Bipolar Disorder
J Clin Psychiatry 2008;69(suppl 3):31-37
© Copyright 2014 Physicians Postgraduate Press, Inc.
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Controlled trials have demonstrated the efficacy of several classes of
drugs for achieving acute response in bipolar mania and depression. For many
years, clinical response has been the primary outcome in the majority of
short-term efficacy studies. However, there is a growing consensus that the
optimal goal in the long-term management of bipolar disorder is remission. The
purpose of this article is to briefly summarize the clinical importance of
remission in bipolar disorder and to review data on the effectiveness of
available treatments for achieving and sustaining remission.