Introduction: The Relationship of Chronic Pain and Depression

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Clinical depression manifests itself in various emotional and physical symptoms, often including chronic physical pain. The comorbidity of chronic pain and chronic depression is so common and the conditions are so interwoven that it is difficult to pinpoint which usually comes first or whether one causes the other; still, the correlation is clear. Almost half of all people with depression experience comorbid somatic symptoms of pain and discomfort.1,2​​

J Clin Psychiatry 2004;65(suppl 12):3-4