Treatment and Outcomes in Adolescents With Schizophrenia
S. Charles Schulz, M.D., Robert L. Findling, M.D.,
Lee Friedman, Ph.D., John T. Kenny, Ph.D., and Alexandria L. Wise
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The pharmacologic treatment and assessment of outcomes in adolescents with schizophrenia have
been inadequately addressed. Structural brain imaging and brain function studies both point to a continuity
between adolescent and adult stages of schizophrenia. Because the teenage population seems
to be less tolerant of physical side effects, the advent of atypical antipsychotic medications may offer
increased safety and efficacy. Studies support the notion that adolescent illness is associated with a
more severe form of schizophrenia and that length of illness before treatment is correlated with longterm
outcome. As a consequence, the authors recommend assertive pharmacologic intervention in
adolescents with schizophrenia and future research focused on the issues of treatment and outcome in
teenagers suffering a psychotic disorder.
J Clin Psychiatry 1998;59(suppl 1):50–54
© Copyright 1998 Physicians Postgraduate Press, Inc.
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