Depression in Asthma: Prevalence and Clinical Implications.
Primary Care Companion J Clin Psychiatry 2000;2(5):153-158
© Copyright 2017 Physicians Postgraduate Press, Inc.
Background: Asthma and depression are both
common illnesses. Data suggest that the prevalence of asthma and
asthma-related morbidity and mortality has increased in the past
2 decades. Asthma has long been considered an illness in which
mood and emotions contribute to symptom exacerbation. Therefore,
we reviewed the recent literature on depression in persons with
Data Sources: The MEDLINE (1966-1999) and
PSYCHINFO (1967-1999) databases were used to find
English-language articles on asthma and depression. Search terms
included asthma, depression, dysthymia, and mood.
Data Synthesis: This literature suggests
depressive symptoms are more common in asthma patients than in
the general population and perhaps even more common than in some
other general medical conditions. Depression may be associated
with asthma morbidity and mortality. Limited data suggest the
older tricyclic antidepressants may improve both depression and
asthma symptoms. However, no studies have examined the use of
second-generation antidepressants in asthma patients.
Conclusion: Depressive symptoms are common in
asthma patients. However, the prevalence of depressive disorders
in this population is not well determined. Future studies should
focus on determining the prevalence of major depressive disorder
in this population and the effect of antidepressants on mood and