The article you requested is

Reply to Searching For Serendipity

J Clin Psychiatry 2011;72(8):1157 [letter]

Letter to the Editor

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I thank Dr Siris for the thoughtful comments and for his innovative suggestions to promote discovery of interventions in psychiatry. Clearly, there is a need for the field of psychopharmacology to identify novel treatments. Unfortunately, the promise of translational research in the search for novel mechanisms of action has yet to be fully realized.