Nitric Oxide Physiology and Pharmacology
J Clin Psychiatry 1998;59(3):101-102
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Issue: Nitric oxide gas (NO) is an unconventional neurotransmitter that is synthesized upon demand. In the brain, it may allow postsynaptic elements to talk back to presynaptic neurons. In peripheral tissues it mediates smooth muscle relaxation. Various pharmacologic agents can enhance or reduce the actions of NO.