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Substance P and the Neurokinins: Novel Peptide Neurotransmitters in Psychopharmacology

J Clin Psychiatry 1999;60(2):77-78
10.4088/JCP.v60n0202

This month’s feature is the second of a 3-part series on peptides and psychiatry. Part 1 appeared last month as a visual lesson on neuropeptide neurotransmitter synthesis, storage, and release in the central nervous system. Part 2 is presented here and explores a specific family of neuropeptides and their receptors, known as neurokinins, of which substance P is the best known example.