Predictors of Quality of Life in Major Psychoses: A Naturalistic Follow-Up Study
J Clin Psychiatry 2003;64(3):308-315
© Copyright 2017 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Background: Improved quality of life (QOL) of
patients suffering from major psychoses has become an important
treatment goal. We sought to determine predictors of perceived
QOL and to explore the changes that occur regarding QOL among
individuals with schizophrenia as compared to patients with
Method: In a naturalistic longitudinal design,
148 inpatients with schizophrenia and 51 inpatients with
schizoaffective/mood disorders (DSM-IV) were tracked for 16
months (SD = 4.6 months). Subjects were assessed at 2 timepoints
for psychopathology, stress process-related factors, and
perceived QOL, as measured by the Quality of Life Enjoyment and
Satisfaction Questionnaire. Predictors of fluctuations in QOL
index scores during the follow-up period were identified using
multiple regression techniques.
Results: We found that poor QOL is
not a more severe problem for schizophrenia patients than for
schizoaffective/mood disorder patients. Improved QOL of
schizophrenia patients is associated with reduced paranoid and
distress (obsessiveness, somatization) symptoms and increased
self-efficacy and self-esteem ratings. Individual changes in QOL
index scores among patients with schizoaffective/mood disorders
are associated with changes in depression, sensitivity, expressed
emotion, and task-oriented coping scores.
Conclusion: Predictors of changes in
satisfaction with life quality over time among schizophrenia
patients are distinct from those associated with
schizoaffective/mood disorders. Changes in stress process-related
factors, rather than psychopathology, predict change in perceived
QOL and should be considered when evaluating QOL outcomes.