Guideline 7: Psychotic Major Depressive Disorder




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To diagnose psychotic major depression in an older patient, the experts required the presence of both delusions and the following three key depressive symptoms: depressed mood, most of the day, every day, markedly diminished interest or pleasure in activities, and recurrent thoughts of death or suicidal ideation or behavior (see Guideline 6A).

The treatment of choice for psychotic major depression in an older patient was an antipsychotic plus an antidepressant, which was rated first line by 98% of the experts.​​

J Clin Psychiatry 2004;65(suppl 2):29-29