Metabolic Syndrome and Depression: A Cross-Sectional Analysis
J Clin Psychiatry 2006;67(9):1422-1427
© Copyright 2014 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Objective: To examine the prevalence of
the metabolic syndrome in depressive outpatients
and to identify its correlates in depression.
Method: This cross-sectional analysis
was performed on 121 depressive outpatients from January 2002 through January 2004 who
were diagnosed at baseline with the Structured
Clinical Interview for DSM-III-R. The metabolic
syndrome was diagnosed at 6-year follow-up according to the modified criteria of the National
Cholesterol Education Program. The severity of depressive symptoms was assessed at
follow-up with the Beck Depression Inventory and
the Hamilton Rating Scale for Depression, and general psychopathology was assessed with
the Symptom Checklist-90.
Results: At 6-year follow-up, the
prevalence of metabolic syndrome in the study group of
depressive outpatients was 36% (N = 44). The syndrome was associated with a current diagnosis
of major depression and overeating, but not with
age or sex.
Conclusion: The metabolic syndrome
is highly prevalent among patients with a history
of depression, especially those with current major depression. This may have implications for
treatment. Furthermore, attention should be
focused on the physical health of those suffering