Intranasal Ketamine for Intermittent Explosive Disorder: A Case Report

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Sir: Ketamine is an N-methyl-D-aspartate blocker. Nasal administration has been used successfully to abort one type of paroxysmal neurologic disorder, namely migraine.1,2 This case describes successful use to abort rage episodes refractory to multiple medical and behavioral interventions.​​

J Clin Psychiatry 2007;68(8):1305