What Clinicians Need to Know About Neuroprotective Issues in Bipolar Disorder
J Clin Psychiatry 2007;68(12):e29
© Copyright 2014 Physicians Postgraduate Press, Inc.
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Neuroimaging and pathohistologic research may show whether bipolar disorder is a
degenerative and progressive condition, if detectable changes in the brain
record past occurrences, and whether these changes are reversible. Interpreting
neuroimaging studies has been complicated by a lack of identification of patient
mood states and differences in patients’ medication status, but several
observations have been made. Pathohistologic research suggests that bipolar
disorder is associated with significant cell pathology.
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