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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Is It Munchausen or Is It Dementia?
Case Report

May 15, 2025

This case elucidates the diagnostic challenges associated with differentiating frontotemporal dementia from aggravating personality disorder or behavioral variant frontotemporal dementia.
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PCC
Role of GLP-1 Receptor Agonists in AUD
Narrative Review

May 15, 2025

The authors examine the potential benefits, dosages, and mechanisms of GLP-1 receptor agonists on alcohol consumption and how they can potentially modify alcohol-seeking behavior.
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PCC
Absconding During Psychiatric Inpatient Treatment
Original Research

May 13, 2025

The study highlights the importance of early risk identification, increased supervision during high-risk periods, and tailored interventions addressing clinical and organizational factors associated with absconding.
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PCC
Seasonality of Australian Medicare-Reimbursed Psychiatric Consultations
Original Research

May 8, 2025

Conventional (face-to-face) office-based psychiatric consultations show clear seasonal changes, especially among young patients, which may have a practical impact on psychiatric service planning.
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PCC
Sequelae of Adverse Childhood Experiences
Rounds in the General Hospital

May 6, 2025

Long-term complications of ACEs involve psychiatric and medical conditions, such as mood and substance use disorders, chronic heart and lung diseases, obesity, diabetes, cancer, and PTSD.
, , , et al
PCC
Risperidone Long-Acting Injection Reduced Emergency Visits in a Patient With Comorbid Autism Spectrum and Borderline Personality Disorders
Case Report

May 1, 2025

This case demonstrates that LAI risperidone may support emotional and interpersonal improvements in a patient with both borderline personality disorder and autism spectrum disorder.
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Vol 27 • 2025 • Number 2

Read the Current Issue

Original Research

What Internists and Neurologists Know and Think About Catatonia

Original Research

Psychological Morbidities in Hospital Staff During Nipah Virus

Systematic Review

Exercise and Fibromyalgia Pain

Rounds in the General Hospital

Managing Anxiety, Agitation, and Pain in Critically Ill Patients

Review Article

Quality Indicators in Community Mental Health Services: A Scoping Review

Case Report

Is My Patient Diverting Their Lorazepam?
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Rounds in the General Hospital Rounds from Banner Alzheimer's Institute

Original Research

PCC
Association of Pregnancy-Related Anxiety With Perceived Social Support: An Observational Study Among Third-Trimester Antenatal Women
Original Research

March 20, 2025

Late-pregnancy anxiety was linked to perceived social support, and specific pregnancy-related anxiety themes, such as concerns about giving birth, the child’s health, one’s own appearance, correlated with distinct perceived…
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PCC
Sleepiness in Colombian Medical Students
Original Research

February 18, 2025

This study investigated the prevalence of sleepiness and associated variables among medical students at a university in Santa Marta, Colombia.
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PCC
Medical Education and the COVID-19 Pandemic
Original Research

February 11, 2025

The pandemic disrupted traditional undergraduate medical education and required adaptations to the clerkship curriculum, such as integration of virtual patient care and telehealth services, to provide meaningful learning experiences.
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Review Articles

PCC
Dextromethorphan-Quinidine for Agitation in Dementia
Narrative Review

November 14, 2024

The authors provide an updated summary of the literature on dextromethorphan-quinidine for the treatment of agitation in patients with dementia.
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PCC
Improving Collaboration Between Neuropsychology and Primary Care
Narrative Review

October 31, 2024

Collaboration between neuropsychologists and physicians significantly improves patient care by enhancing diagnostic precision and treatment planning. Read on to find out more.
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PCC
Understanding the Child and Adolescent Mental Health Crisis
Narrative Review

October 24, 2024

The authors delve into current mental health challenges facing children and youth, examining perspectives from both pre-pandemic and pandemic periods.
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PCC
Management of Sleep Disturbances in Veterans Following Mild TBI
Narrative Review

September 12, 2024

The authors developed an evidence- and consensus-based clinical recommendation regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury in service members and veterans.
, , , et al
PCC
Management of ADHD in Adolescents and Young Adults
Narrative Review

August 6, 2024

Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and…
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PCC
Tech Gaming Designs, Neurodevelopmental Vulnerabilities, and Internet Gaming Disorder Risk
Narrative Review

July 23, 2024

The authors review the relevant research in the field of internet gaming disorder and provide an approach to identification and management.
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Rounds in the General Hospital

PCC
Wishing That Your Patient Would Die: Reasons and Reactions
Rounds in the General Hospital

February 25, 2025

The authors explore the complexity, intensity, and critical decision-making faced by health care staff while caring for chronically and critically ill patients, especially in the context of medical futility.
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PCC
Psychosis-Related PTSD
Rounds in the General Hospital

February 6, 2025

Frightening psychotic experiences might serve as traumatic events and precipitate development of PTSD, and the first step to successful management is ensuring a proper assessment.
, , , et al
PCC
Prolonged Grief: Etiology and Management
Rounds in the General Hospital

February 4, 2025

Prolonged grief disorder has several features that overlap with depression and PTSD but is a distinct entity for which a well-validated, targeted treatment is available.
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PCC
Management of Insomnia in the General Hospital
Rounds in the General Hospital

January 21, 2025

Although the etiology of insomnia is often multi-factorial, both nonpharmacologic and various pharmacologic approaches can provide rapid relief; unfortunately, each is associated with drug-drug interactions and potentially problematic side…
, , , et al
PCC
Focal Impaired Awareness Seizures: Evaluation and Management
Rounds in the General Hospital

January 3, 2025

Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the changes in affect, behavior, and cognition, are often misdiagnosed as a primary…
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PCC
Comorbid Bipolar Disorder and PTSD
Rounds in the General Hospital

December 24, 2024

Bipolar disorder and PTSD are highly comorbid conditions, and pharmacologic management poses unique challenges, as side effects of the commonly used medications for one disorder can worsen the symptoms…
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Case Reports

PCC
Pirfenidone-Induced Fear of Forgetting
Case Report

May 1, 2025

The authors report an unusual association of pirfenidone and athazagoraphobia, leading to its discontinuation in idiopathic pulmonary fibrosis.
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PCC
Delusions of Parasitosis With Methylphenidate
Case Report

April 29, 2025

A 70-year-old woman developed delusions of parasitosis extended-release methylphenidate after taking it for more than 6 years.
PCC
Neuropsychiatric Presentation of Vitamin B12 Deficiency
Case Report

April 24, 2025

This case describes a 59-year-old woman with borderline B12 deficiency presenting with only neuropsychiatric symptoms
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PCC
Shock Anxiety After Electrical Storm Treated With CBT
Case Report

April 24, 2025

A patient with arrhythmogenic right ventricular dysplasia/cardiomyopathy, who had recently experienced electrical storm from her implantable cardioverter-defibrillator, developed shock anxiety with phobic avoidance.
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PCC
Secondary Delusional Infestation in a Male with a History of Polysubstance Use
Case Report

April 22, 2025

A 20-year-old man with a history of polysubstance use presented to the ED with a severe pruritic lesion in the left scapular region. Over the past 22 days, he…
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PCC
Oxcarbazepine/Aripiprazole Interaction and Bipolar Relapse
Case Report

April 10, 2025

This case highlights the interaction between aripiprazole and oxcarbazepine, resulting in subtherapeutic levels of aripiprazole and recurrence of manic symptoms in a patient with bipolar I disorder.
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Letter to the Editor

PCC
Revisiting Ayahuasca: Vine of the Soul of the Amazon
Letter to the Editor

March 18, 2025

The authors comment on a case report previously published in the PCC describing psychosis and ayahuasca use and discuss the need for further research given its increased usage worldwide.
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PCC
Cannabis Withdrawal Psychosis
Letter to the Editor

March 13, 2025

Dr Gorelick comments on a case report recently published in the PCC.
PCC
Cannabis Withdrawal Psychosis: Reply to Gorelick
Letter to the Editor

March 13, 2025

The authors reply to a letter to the editor commenting on their case report.
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PCC
Parenting Young Adults With ADHD
Letter to the Editor

February 13, 2025

The authors explore the role of parental involvement in supporting young adults with ADHD.
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PCC
Letter to the Editor

December 10, 2024

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PCC
Is Bariatric Surgery an Antidepressant?
Letter to the Editor

October 29, 2024

The effect of bariatric surgery on mood disorders is uncertain. Read on to find out more.

More Articles from The Primary Care Companion for DNS Disorders

PCC
First-Episode Psychosis and Cushing Syndrome
Case Report

March 25, 2025

A 72-year-old man with no prior psychiatric history was diagnosed with new-onset psychosis in the setting of hypercortisolism.
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PCC
Thought Broadcasting and Cultural Beliefs
Case Report

March 18, 2025

A 42-year-old woman attributed her thought broadcasting to the possession of a Ruhani, a type of jinn believed to have the power to influence human thoughts and behaviors.
PCC
Biofeedback for Functional Vomiting Management
Case Report

March 11, 2025

The authors describe 2 patients who responded to biofeedback-based behavioral interventions for functional vomiting.
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PCC
A Tale of 2 Lithium Toxicities
Case Report

March 11, 2025

The authors report the cases of 2 patients, both with lithium toxicity; however, the clinical manifestations were paradoxical.
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PCC
Substance Use in Pregnant and Postpartum Women
Brief Report

March 6, 2025

This study calculated the prevalence of substance use disorder diagnosis among pregnant and postpartum visits in 2020 using inpatient and ED data from the National Hospital Care Survey.
, , , et al
PCC
Pediatric Postinfectious Cranial Neuropathy
Case Report

March 6, 2025

A 14-year-old boy developed acute nasal regurgitation and dysphonia following a febrile illness.
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PCC
Ketamine-Associated Psychosis After Surgery
Case Report

March 4, 2025

The authors present a unique case of extended postoperative psychosis after intraoperative ketamine induction for analgesia.
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PCC
Challenges in Adult Patients With ARFID
Case Report

March 4, 2025

This case report highlights the need for individualized treatment protocols for adult patients with avoidant-restrictive food intake disorder
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PCC
Thyrotoxic Psychosis in Graves’ Disease
Case Report

February 27, 2025

A patient with a 2-year history of Graves’ disease and nonadherent to anti-thyroid treatment developed mania with psychosis.
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PCC
Factitious Disorder in the Context of Abuse in an Adolescent
Case Report

February 27, 2025

This case illustrates the complexities of diagnosing factitious disorder in adolescents, in which psychosocial factors play a significant role.
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PCC
Frontal Lobe Syndrome Unveils an Unexpected Diagnosis
Case Report

February 20, 2025

A 55-year-old man was admitted to the psychiatric ED due to changes in behavior, posing risk to himself and to others, and refusing medical assistance. A CT scan revealed…
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PCC
Low-Dose Clozapine in Schizophrenia With Aggression
Case Report

February 20, 2025

A patient with schizophrenia with significant aggression achieved remission with a low dose of clozapine started after the first failed antipsychotic trial.
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