MY ACCOUNT
JCP
Risk Factors for Reattempt and Suicide Within 6 Months After an Attempt in the French ALGOS Cohort: A Survival Tree Analysis
Understanding risk factors for suicidal behavior is crucial for the development of effective prevention plans. Do anxiety disorders or alcohol use disorder play a role? Learn more in this CME activity.
N-Acetylcysteine Augmentation for Patients With Major Depressive Disorder and Bipolar Depression
Two recent meta-analyses found little effect of N-acetylcysteine augmentation in MDD or bipolar depression, although some past research has indicated its efficacy. In this article, Dr Andrade takes a closer look at whether the evidence supports its use.
HARKing, Cherry-Picking, P-Hacking, Fishing Expeditions, and Data Dredging and Mining as Questionable Research Practices
In this article, Dr Andrade helps readers identify several types of statistical analysis that violate scientific principles and that researchers may knowingly—or unknowingly—engage in.
How Much Is the Debate Over Antidepressant Efficacy and Safety in Bipolar Depression an Artifact of Study Methodologies?
This editorial discusses a recent study of citalopram in bipolar depression and revisits the long-held assumption that antidepressants lead to poor outcomes in bipolar disorder.
Dr Andrade Replies
Here, Dr Andrade replies to a letter to the editor regarding a recent Clinical and Practical Psychopharmacology column on use of baclofen in alcohol use disorder patients.
Effects of Long-Acting Injectable Paliperidone Palmitate on Clinical and Functional Outcomes in Patients With Schizophrenia Based on Illness Duration
Although long-acting injectable (LAI) antipsychotics show benefit in the early stages of schizophrenia, they are mostly used later in the illness. This study assessed clinical and functional improvement with paliperidone LAI at different illness durations.
Citalopram for Acute and Preventive Efficacy in Bipolar Depression (CAPE-BD): A Randomized, Double-Blind, Placebo-Controlled Trial
Antidepressants are widely used to treat bipolar illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of citalopram in bipolar depression.
Optimal Long-Acting Injectable Antipsychotic Management During COVID-19
Long-acting injectable antipsychotics are effective for preventing relapse in schizophrenia, but in-person administration of them is a challenge during a pandemic. This report describes how a clinic successfully reduced in-person injections by 40%.
Baclofen, a French Exception, Seriously Harms Alcohol Use Disorder Patients Without Benefit
In this letter to the editor, the authors comment on a Clinical and Practical Psychopharmacology article recently published in JCP.
Associations Between ADHD Medication Use in Pregnancy and Severe Malformations Based on Prenatal and Postnatal Diagnoses: A Danish Registry-Based Study
Do you have patients who take ADHD medication and are planning a pregnancy? How do you respond to questions of safety? This journal CME activity offers evidence.
