Pharmacotherapy for Patients With Fibromyalgia
J Clin Psychiatry 2008;69(suppl 2):25-29
© Copyright 2015 Physicians Postgraduate Press, Inc.
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Fibromyalgia is a common and disabling syndrome. Despite research
detailing the efficacy of a variety of medicinal treatments, most notably,
tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, and
α2δ ligands, there is still widespread, routine use of
agents that are mostly ineffective in treating the central nature of
fibromyalgic pain. This article discusses pharmacotherapeutic options for
fibromyalgia, including those with high-level evidence for efficacy,
moderate-level evidence, and little or no evidence for efficacy. The
importance of an integrated treatment approach that includes pharmacotherapy
and at least one, but preferably more, of the most effective nonmedicinal
treatment options available (e.g., education, aerobic exercise, and
cognitive-behavioral therapy) is also discussed.