Refractory Generalized Anxiety Disorder
J Clin Psychiatry 2009;70(suppl 2):32-38
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Generalized anxiety disorder (GAD) has a lifetime prevalence in the US population of about 5.7%.
Typically, GAD begins in early adulthood and tends to have a chronic and persistent course. The disorder
frequently presents comorbidly with other conditions, and about 90% of patients with GAD
have at least 1 comorbid lifetime psychiatric disorder. Patients with GAD tend to be high users of
medical services; the disorder is associated with significant physical as well as psychological symptomatology
and impacts health, family relationships, and employment. Pharmacologic and psychosocial
treatments are available for GAD.