Original Research J Clin Psychiatry March 2013

Randomized Controlled Trial of Mindfulness Meditation for Generalized Anxiety Disorder: Effects on Anxiety and Stress Reactivity

JCP 2013;74(8):10.4088/JCP.12m08083

Full Article Read the complete peer-reviewed article in J Clin Psychiatry. JCP 2013;74(8):10.4088/JCP.12m08083 Clinical Summary Many patients with generalized anxiety disorder remain symptomatic despite standard treatment, and some avoid specialty psychiatric care altogether. This trial tests whether a structured mindfulness program offers benefit beyond a time- and attention-matched stress education intervention, with outcomes that matter clinically: anxiety, sleep, and response to acute stress. FAQ Does mindfulness meditation help generalized anxiety disorder? 12 questions
Key Takeaways This active-control design tested MBSR against a time- and attention-matched stress education program rather than a wait-list, making the between-group differences on CGI-S, CGI-I, and BAI more clinically persuasive than findings from uncontrolled mindfulness studies. 6 takeaways
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