Medical Risk in Patients With Bipolar Disorder and Schizophrenia
J Clin Psychiatry 2006;67(suppl 9):25-30
© Copyright 2014 Physicians Postgraduate Press, Inc.
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Patients with schizophrenia and bipolar disorder are vulnerable to developing key modifiable risk
factors for cardiovascular disease, such as obesity, smoking, hypertension, dyslipidemia, and type 2
diabetes mellitus. In addition, mood stabilizers, anticonvulsants, and antipsychotic medications,
which are commonly used to treat schizophrenia and bipolar disorder, have been linked to risk for
adverse metabolic changes in patients. This article reviews the current literature on the prevalence of
medical risk factors in the general population as well as in those patients with schizophrenia or bipolar
disorder and discusses treatment strategies and lifestyle changes that patients can make in order to
reduce their risks for certain diseases.