Preventing Recurrent Depression: Long-Term Treatment for Major Depressive Disorder.

First page of Academic Highlights: Preventing Recurrent Depression: Long-Term Treatment for Major Depressive Disorder. [CME]

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Major depressive disorder (MDD) is a recurrent or chronic disorder in many patients. Patients who receive inadequate treatment and fail to reach remission are at risk for poor longterm outcomes, including ongoing morbidity and mortality from other psychiatric and medical conditions, impaired psychosocial function, and increased tendency to relapse. While safe and effective treatments exist for major depressive disorder, until recently there was only limited evidence on how to successfully treat patients who do not achieve remission after a single course of antidepressant treatment or who respond but then experience recurrent episodes.

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J Clin Psychiatry 2007;68(4):619-630