Preventing Recurrent Depression: Long-Term Treatment for Major Depressive Disorder

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Major depressive disorder (MDD) is potentially a long-term or even lifelong illness for many patients, and maintenance therapy is designed to prevent relapse in patients with recurrent depression who have achieved remission. Patients who have residual symptoms, ongoing psychosocial stressors, or comorbid illnesses are among the suitable candidates for maintenance treatment. In the following discussion, experts in the treatment of depression address topics relevant to maintenance treatment: length of treatment, pharmacotherapy dosage, psychotherapy, and electroconvulsive therapy (ECT).​

Prim Care Companion J Clin Psychiatry 2007;9(3):214-223