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Pharmacologic Principles in Using Antipsychotics: Application in Clinical Practice Sheldon H. Preskorn, MD (Chair), et al

Update your understanding of the pharmacologic principles of antipsychotics to achieve the best treatment outcomes.

>>See the entire activity

Preventing Relapse in Bipolar Disorder Alan C. Swann, MD

NEW! In this activity, learn about strategies to prevent or delay recurrence during the maintenance phase of bipolar disorder treatment.

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Articles published electronically 8/24/10

Armodafinil as Adjunctive Therapy in Adults With Cognitive Deficits Associated With Schizophrenia: A 4-Week, Double-Blind, Placebo-Controlled Study

[Abstract] [Full Text] Posted 8/24/10

Orlistat in Clozapine- or Olanzapine-Treated Patients With Overweight or Obesity: A 16-Week Open-Label Extension Phase and Both Phases of a Randomized Controlled Trial

[Abstract] [Full Text] Posted 8/24/10

Enhanced Prefrontal Function With Pharmacotherapy on a Response Inhibition Task in Adolescent Bipolar Disorder

[Abstract] [Full Text] Posted 8/24/10

Analysis of Suicidality in Pooled Data From 2 Double-Blind, Placebo-Controlled Aripiprazole Adjunctive Therapy Trials in Major Depressive Disorder

[Abstract] [Full Text] Posted 8/24/10

White Matter Hyperintensities, Medial Temporal Lobe Atrophy, Cortical Atrophy, and Response to Electroconvulsive Therapy in Severely Depressed Elderly Patients

[Abstract] [Full Text] Posted 8/24/10

Acute Efficacy of Divalproex Sodium Versus Placebo in Mood Stabilizer–Naive Bipolar I or II Depression: A Double-Blind, Randomized, Placebo-Controlled Trial

[Abstract] [Full Text] Posted 8/24/10

Twelve-Month Prevalence of and Risk Factors for Suicide Attempts in the World Health Organization World Mental Health Surveys

[Abstract] [Full Text] Posted 8/24/10

Health-Related Quality of Life Across the Anxiety Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

[Abstract] [Full Text] Posted 8/24/10

Lifetime Prevalence of Mood and Anxiety Disorders in Fragile X Premutation Carriers

[Abstract] [Full Text] Posted 8/24/10

Articles published electronically 8/10/10

Treatment Outcomes of Patients With Tardive Dyskinesia and Chronic Schizophrenia

[Abstract] [Full Text] Posted 8/10/10

Double-Blind, Placebo-Controlled Trial of Topiramate Augmentation in Treatment-Resistant Obsessive-Compulsive Disorder

[Abstract] [Full Text] Posted 8/10/10

Pharmacotherapy for the Treatment of Acute Bipolar II Depression: Current Evidence

[Abstract] [Full Text] Posted 8/10/10

Pain Inhibition Is Deficient in Chronic Widespread Pain but Normal in Major Depressive Disorder

[Abstract] [Full Text] Posted 8/10/10

Representativeness of Participants in a Clinical Trial for Attention-Deficit/Hyperactivity Disorder? Comparison With Adults From a Large Observational Study

[Abstract] [Full Text] Posted 8/10/10

Suicidality as Rare Adverse Event of Antidepressant Medication: Report From the AMSP Multicenter Drug Safety Surveillance Project

[Abstract] [Full Text] Posted 8/10/10

Detection of Subclinical Depression in Bipolar Disorder: A Cross-Sectional, 4-Month Prospective Follow-Up Study at Community Mental Health Services (SIN-DEPRES)

[Abstract] [Full Text] Posted 8/10/10

Do Efficacy and Effectiveness Samples Differ in Antidepressant Treatment Outcome? An Analysis of Eligibility Criteria in Randomized Controlled Trials

[Abstract] [Full Text] Posted 8/10/10

A Prospective Study of Hormone Therapy and Depression in Community-Dwelling Elderly Women: The Three City Study

[Abstract] [Full Text] Posted 8/10/10

Articles published electronically 7/27/10

Adjunctive Armodafinil for Major Depressive Episodes Associated With Bipolar I Disorder: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Proof-of-Concept Study

[Abstract] [Full Text] Posted 7/27/10

A Double-Blind, Randomized Study Comparing the Efficacy and Safety of Sertindole and Risperidone in Patients With Treatment-Resistant Schizophrenia

[Abstract] [Full Text] Posted 7/27/10

Articles published electronically 7/13/10

Reduced Anterior Cingulate and Orbitofrontal Volumes in Child Abuse–Related Complex PTSD

[Abstract] [Full Text] Posted 7/13/10

Long-Acting Injectable Versus Oral Naltrexone Maintenance Therapy With Psychosocial Intervention for Heroin Dependence: A Quasi-Experiment

[Abstract] [Full Text] Posted 7/13/10

Identifying Depressive Subtypes in a Large Cohort Study: Results From the Netherlands Study of Depression and Anxiety (NESDA)

[Abstract] [Full Text] Posted 7/13/10

Two Clinical Trial Designs to Examine Personalized Treatments for Psychiatric Disorders

[Abstract] [Full Text] Posted 7/13/10

McLean-Harvard International First-Episode Project: Two-Year Stability of ICD-10 Diagnoses in 500 First-Episode Psychotic Disorder Patients

[Abstract] [Full Text] Posted 7/13/10

Rapid Resolution of Suicidal Ideation After a Single Infusion of an N-Methyl-d-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

[Abstract] [Full Text] Posted 7/13/10

Articles published electronically 6/29/10

Shared Neural Activity in Panic Disorder and Undifferentiated Somatoform Disorder Compared With Healthy Controls

[Abstract] [Full Text] Posted 6/29/10

Antipsychotic Medication and Oxidative Cell Stress: A Systematic Review

[Abstract] [Full Text] Posted 6/29/10

Fluoxetine Treatment of Alcoholic Perpetrators of Domestic Violence: A 12-Week, Double-Blind, Randomized, Placebo-Controlled Intervention Study

[Abstract] [Full Text] Posted 6/29/10

Relapse Prevention in First-Episode Schizophrenia—Maintenance vs Intermittent Drug Treatment With Prodrome-Based Early Intervention: Results of a Randomized Controlled Trial Within the German Research Network on Schizophrenia

[Abstract] [Full Text] Posted 6/29/10

Subsyndromal Depressive Symptoms After Symptomatic Recovery From Mania Are Associated With Delayed Functional Recovery

[Abstract] [Full Text] Posted 6/29/10

Effects of Atomoxetine With and Without Behavior Therapy on the School and Home Functioning of Children With Attention-Deficit/Hyperactivity Disorder

[Abstract] [Full Text] Posted 6/29/10

Articles published electronically 6/15/10

A Cohort Study of the Prevalence and Impact of Comorbid Medical Conditions in Pediatric Bipolar Disorder

[Abstract] [Full Text] Posted 6/15/10

The Efficacy of Omega-3 Supplementation for Major Depression: A Randomized Controlled Trial

[Abstract] [Full Text] Posted 6/15/10

Determinants of Poor Dental Care in Patients With Schizophrenia: A Historical, Prospective Database Study

[Abstract] [Full Text] Posted 6/15/10

Pregnenolone and Dehydroepiandrosterone as an Adjunctive Treatment in Schizophrenia and Schizoaffective Disorder: An 8-Week, Double-Blind, Randomized, Controlled, 2-Center, Parallel-Group Trial

[Abstract] [Full Text] Posted 6/15/10

Personality Disorders Predict Relapse After Remission From an Episode of Major Depressive Disorder: A 6-Year Prospective Study

[Abstract] [Full Text] Posted 6/15/10

Articles published electronically 6/1/10

Trauma Exposure and Posttraumatic Stress Disorder in Primary Care Patients: Cross-Sectional Criterion Standard Study

[Abstract] [Full Text] Posted 6/1/10

Abnormal Integrity of Long Association Fiber Tracts Is Associated With Cognitive Deficits in Patients With Remitted Geriatric Depression: A Cross-Sectional, Case-Control Study

[Abstract] [Full Text] Posted 6/1/10

Persistent Depressive Symptoms and Cognitive Function in Late Midlife: The Whitehall II Study

[Abstract] [Full Text] Posted 6/1/10

A Systematic Review of Aripiprazole—Dose, Plasma Concentration, Receptor Occupancy, and Response: Implications for Therapeutic Drug Monitoring

[Abstract] [Full Text] Posted 6/1/10

Two-Year Outcome of Treatment With Central Stimulant Medication in Adult Attention-Deficit/Hyperactivity Disorder: A Prospective Study

[Abstract] [Full Text] Posted 6/1/10

Articles published electronically 5/18/10

Impact of Attention-Deficit/Hyperactivity Disorder (ADHD) Treatment on Smoking Cessation Intervention in ADHD Smokers: A Randomized, Double-Blind, Placebo-Controlled Trial

[Abstract] [Full Text] Posted 5/18/10

Articles published electronically 5/4/10

Metabolic Syndrome in Patients Enrolled in a Clinical Trial of Aripiprazole in the Maintenance Treatment of Bipolar I Disorder: A Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial

[Abstract] [Full Text] Posted 5/4/10

Characteristics of the Retrospectively Assessed Prodromal Period in Hospitalized Patients With First-Episode Nonaffective Psychosis: Findings From a Socially Disadvantaged, Low-Income, Predominantly African American Population

[Abstract] [Full Text] Posted 5/4/10

Patient Overcrowding in Hospital Wards as a Predictor of Diagnosis-Specific Mental Disorders Among Staff: A 2-Year Prospective Cohort Study

[Abstract] [Full Text] Posted 5/4/10

The Neurobiology of the Switch Process in Bipolar Disorder: A Review

[Abstract] [Full Text] Posted 5/4/10

Articles published electronically 4/20/10

Risk Predictors for Hypnosedative-Related Complex Sleep Behaviors: A Retrospective, Cross-Sectional Pilot Study

[Abstract] [Full Text] Posted 4/20/10

Orally Disintegrating and Oral Standard Olanzapine Tablets Similarly Elevate the Homeostasis Model Assessment of Insulin Resistance Index and Plasma Triglyceride Levels in 12 Healthy Men: A Randomized Crossover Study

[Abstract] [Full Text] Posted 4/20/10

A Randomized Controlled Trial of Risperidone and Olanzapine for Schizophrenic Patients With Neuroleptic-Induced Tardive Dyskinesia

[Abstract] [Full Text] Posted 4/20/10

A Randomized, Double-Blind, Placebo-Controlled Trial of Olanzapine in the Treatment of Trichotillomania

[Abstract] [Full Text] Posted 4/20/10

A Randomized Controlled Trial of Antidepressant Continuation for Major Depression Following Traumatic Brain Injury

[Abstract] [Full Text] Posted 4/20/10

Articles published electronically 4/6/10

The Association Between Income and Distress, Mental Disorders, and Suicidal Ideation and Attempts: Findings From the Collaborative Psychiatric Epidemiology Surveys

[Abstract] [Full Text] Posted 4/6/10

The Effect of Metformin on Anthropometrics and Insulin Resistance in Patients Receiving Atypical Antipsychotic Agents: A Meta-Analysis

[Abstract] [Full Text] Posted 4/6/10

A Cross-Sectional Study of Vitamin D Deficiency Among Immigrants and Norwegians With Psychosis Compared to the General Population

[Abstract] [Full Text] Posted 4/6/10

A Randomized Controlled Trial of the Safety and Promise of Cognitive-Behavioral Therapy Using Imaginal Exposure in Patients With Posttraumatic Stress Disorder Resulting From Cardiovascular Illness

[Abstract] [Full Text] Posted 4/6/10

Cytochrome P450 2D6 Phenotype Predicts Antidepressant Efficacy of Venlafaxine: A Secondary Analysis of 4 Studies in Major Depressive Disorder

[Abstract] [Full Text] Posted 4/6/10

Articles published electronically 3/23/10

Assertive Community Treatment as Part of Integrated Care Versus Standard Care: A 12-Month Trial in Patients With First- and Multiple-Episode Schizophrenia Spectrum Disorders Treated With Quetiapine Immediate Release (ACCESS Trial)

[Abstract] [Full Text] Posted 3/23/10

Does the Therapy Manual or the Therapist Matter Most in Treatment of Obsessive-Compulsive Disorder? A Randomized Controlled Trial of Exposure With Response or Ritual Prevention in 118 Patients

[Abstract] [Full Text] Posted 3/23/10

Neurocognitive Functioning in Patients With Bipolar I Disorder Recently Recovered From a First Manic Episode

[Abstract] [Full Text] Posted 3/23/10

Screening for Bipolar Disorder and Finding Borderline Personality Disorder

[Abstract] [Full Text] Posted 3/23/10

Articles published electronically 3/9/10

Causes of Aggressive Behavior in Patients With Dementia

[Abstract] [Full Text] Posted 3/9/10

Articles published electronically 2/23/10

Positron Emission Tomography Measurement of Dopamine D2 Receptor Occupancy in the Pituitary and Cerebral Cortex: Relation to Antipsychotic-Induced Hyperprolactinemia

[Abstract] [Full Text] Posted 2/23/10

Prevalence and Correlates of Fire-Setting in the United States: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

[Abstract] [Full Text] Posted 2/23/10

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Volume 71
2010
Number 8

CME Pretest | CME Posttest

NCDEU FESTSCHRIFT

971 The Future of Psychopharmacology of Depression [Keyword: NCDEU]

[Abstract] [Full Text]

Commentary

982 Clozapine: More Side Effects but Still the Best Antipsychotic

[Purchase] [Full Text]

Consensus Statement

1040 Suicidality and Risk of Suicide—Definition, Drug Safety Concerns, and a Necessary Target for Drug Development: A Brief Report

[Abstract] [Full Text]

Online Exclusive

e100 Suicidality and Risk of Suicide—Definition, Drug Safety Concerns, and a Necessary Target for Drug Development: A Consensus Statement [Keyword: Suicide]

[Abstract] [Full Text]

Original Articles

976 Diagnostic Characteristics of Clozapine-Induced Myocarditis Identified by an Analysis of 38 Cases and 47 Controls

[Abstract] [Full Text]

984 Prediction of Recurrence in Recurrent Depression: A 5.5-Year Prospective Study [CME]

[Abstract] [Full Text] [CME Activity]

992 Noninvasive Brain Stimulation With High-Frequency and Low-Intensity Repetitive Transcranial Magnetic Stimulation Treatment for Posttraumatic Stress Disorder

[Abstract] [Full Text]

1000 Why Do Clinicians Maintain Antidepressants in Some Patients With Acute Mania? Hints From the European Mania in Bipolar Longitudinal Evaluation of Medication (EMBLEM), a Large Naturalistic Study

[Abstract] [Full Text]

1007 Inflammatory Biomarkers in 70 Depressed Inpatients With and Without the Metabolic Syndrome

[Abstract] [Full Text]

1017 Neural Processing of Emotional Overinvolvement in Borderline Personality Disorder

[Abstract] [Full Text]

1025 Karolinska Interpersonal Violence Scale Predicts Suicide in Suicide Attempters

[Abstract] [Full Text]

1033 A 2-Year Prospective Follow-Up Study of the Course of Obsessive-Compulsive Disorder [CME]

[Abstract] [Full Text] [CME Activity]

1047 Prevalence and Treatment Outcome in Anxious Versus Nonanxious Depression: Results From the German Algorithm Project

[Abstract] [Full Text]

1055 Lithium Treatment Effects on the Neuropsychological Functioning of Patients With Bipolar I Disorder

[Abstract] [Full Text]

Focus on Women’s Mental Health

1061 Onset and Exacerbation of Obsessive-Compulsive Disorder in Pregnancy and the Postpartum Period

[Abstract] [Full Text]

1069 Are Maternal Depression or Symptom Severity Associated With Breastfeeding Intention or Outcomes?

[Abstract] [Full Text]

1079 Low 24-Hour Adiponectin and High Nocturnal Leptin Concentrations in a Case-Control Study of Community-Dwelling Premenopausal Women With Major Depressive Disorder: The Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) Study

[Abstract] [Full Text]

1088 Short-Term Efficacy and Safety of Desvenlafaxine in a Randomized, Placebo-Controlled Study of Perimenopausal and Postmenopausal Women With Major Depressive Disorder

[Abstract] [Full Text]

ASCP Corner

1097 Bereavement, Complicated Grief, and DSM, Part 2: Complicated Grief

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Letters To the Editor

1099 Posttraumatic Stress Disorder and Health-Related Quality of Life in Pension-Seeking Canadian World War II and Korean War Veterans

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1101 REM Sleep Behavior Disorder in Psychiatric Populations

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Book Reviews

1104 Clinical Manual for Evaluation and Treatment of Sleep Disorders

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1104 Prime Time: Maximizing the Therapeutic Experience: A Primer for Psychiatric Clinicians

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1105 The Medical Basis of Psychiatry, 3rd ed.

[Purchase] [Full Text]

online CME Activities

Posted at www.psychiatrist.com/toc—many in interactive formats

e18 Monitoring Adults With ADHD: A Focus on Executive and Behavioral Function

[Abstract]

e19 Performance Improvement CME: Improving Outcomes in Depression

[Abstract]

e20 Nonpharmacologic Care of Patients With Fibromyalgia

[Abstract]

information for authors

see www.psychiatrist.com/author.htm

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The Journal of Clinical Psychiatry is the official journal of the American Society for Clinical Psychopharmacology

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Editors’ Perspectives: Peer Review and the Evolving Journal

Commentaries on Peer Review and the Evolving Journal. Marlene P. Freeman
[Full Text With Forum]

Peer Review Perspective for Early Career Psychiatrists. Alan J. Gelenberg
[Full Text With Forum]

Learning to Review. Robert Freedman
[Full Text With Forum]

Peer Review by Early Career Psychiatrists: An Opportunity for Development. Anne F. Gross, Ilse R. Wiechers, and Theodore A. Stern
[Full Text With Forum]

The Evolution of the Psychiatry Research Journal. John H. Krystal
[Full Text With Forum]

Peer Review in Early Career: Just Say Yes! Peter P. Roy-Byrne
[Full Text With Forum]

Perspectives on Perinatal Depression Treatment

Perinatal Psychiatry: The Challenges of Making Rational Treatment Decisions at the Interface of Psychiatry and Obstetrics. Marlene P. Freeman
[Full Text With Forum]

Influence of the Media on Women Taking Antidepressants During Pregnancy. Adrienne Einarson
[Full Text With Forum]

The Other Side of the Risk Equation: Exploring Risks of Untreated Depression and Anxiety in Pregnancy. Ellen M. Markus and Laura J. Miller
[Full Text With Forum]

Reflections on Perinatal Depression Treatment. Bryanne Barnett, and Marie-Paule Austin
[Full Text With Forum]

Do We Scare Because We Care? Diane N. Solomon
[Full Text With Forum]

Perinatal Depression: Searching for Specific Tools for a Closer Look at This Window. Claudio N. Soares, and Meir Steiner
[Full Text With Forum]

Psychotherapeutic Treatment Options for Perinatal Depression: Emphasis on Maternal-Infant Dyadic Outcomes. Maria Muzik, Sheila M. Marcus, and Heather A. Flynn
[Full Text With Forum]

No Decision Is Without Risk. Rita Suri, and Lori L. Altshuler
[Full Text With Forum]

The Cost of Restricting Knowledge. Anna R. Brandon, Geetha Shivakumar, Stephen J. Inrig, Simon J. Craddock Lee, and John Z. Sadler
[Full Text With Forum]

Pharmacotherapy or Untreated Antenatal Depression: A False Dichotomy. Sona Dimidjian, and Michael W. O’Hara
[Full Text With Forum]

 
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Early Career Psychiatrists

Marlene P. Freeman, MD (Editor)

Focus on Alzheimer's Disease and Related Disorders

Eric M. Reiman, MD (Editor)

Focus on Childhood and Adolescent Mental Health

Karen D. Wagner, MD, PhD (Editor)

Focus on Women's Mental Health

Marlene P. Freeman, MD (Editor)

ASCP Corner

J. Craig Nelson, MD (Editor)

Brainstorms

Stephen M. Stahl, MD, PhD

Case Reports

NCDEU Festschrift

A Roadmap to Key Pharmacologic Principles in Using Antipsychotics: Application in Clinical Practice

Shelton H. Preskorn, MD (Chair), et al

In this Academic Highlights, learn how the pharmacodynamic and pharmacokinetic properties of antipsychotic medications can help to individualize treatment and achieve the best outcomes for patients.

>>See the entire Academic Highlights

>>See all available Academic Highlights

International Consensus Group on Depression

David J. Nutt, MD, PhD (Chair), et al

In this Supplement, review the current depression guidelines from various countries, learn about appropriate tools to use for your patients with depression, and get the latest treatment recommendations from the international experts in psychiatry.

>>See the entire supplement

>>See all available supplements

CME

Adherence Problems in Patients with Serious and Persistent Mental Illness

Dawn I. Velligan, PhD (Chair), et al

Read this Supplement for answers to your questions about recognizing and addressing adherence problems.

>>See the entire activity

>>See all Journal CME activities

Performance Improvement CME: Managing Chronic Pain

Scott M. Fishman, MD

NEW! Improve chronic pain management by choosing relevant clinical questions and consulting evidence-based references.

>>See the entire activity

>>See all Multimedia activities

Pharmacologic Therapy for Fibromyalgia

Larry Culpepper, MD, MPH

Short summary of pharmacologic options that can help your patients with fibromyalgia feel better and regain function.

>>See the entire activity

>>See all CME Partners activities

Learn. Practice. Treat.

Strategies for the Early Recognition of Bipolar Disorder

Terence A. Ketter, MD

NEW! Learn about the risk factors for bipolar disorder and how to complete a differential diagnosis for this condition.

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Our user-friendly electronic manuscript submission and peer review system allows you to submit your manuscript online securely, conveniently, and instantly. Authors can track the progress of their manuscripts from submission to publication. Assistance is available via e-mail if needed.

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Journal Statistics and Impact Information (updated October 2007)

Journal Statistics

Acceptance rate

 

31%

No. of articles published per issue

 

Mean=16, range=14–22

Submission-to–first decision time (mean)

 

40.9 days

Submission-to–final decision time (mean)

 

51.6 days

Submission-to-acceptance time (estimated average)

 

4 months

Acceptance-to-publication time

 

Mean=5.2 months,
range=3–9 months

Impact Information

The Journal of Clinical Psychiatry continues to be ranked as the most-read and 6th most-cited psychiatric journal in the world (according to the Focus Readership Study, June 2007, and Citation Index, July 2007, respectively). The Journal mails to about 35,184 recipients,* and over 20,000 allied mental health professionals have requested daily receipt of informational e-mails about our journals and Web CME activities.

The JCP is also a member of BPA Worldwide and is the official journal of the American Society of Clinical Psychopharmacology, which consists of 800 members who are biopsychiatric researchers, academicians, and clinicians.

*Source: BPA Circulation Statement, June 2007

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Manuscripts that meet the Journal’s scope and submission criteria are sent to expert consultants for peer review.

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Reviewers who have a financial or personal conflict of interest related to a manuscript are obligated to decline the reviewer position.

Processing of Peer Reviews

The peer review process is conducted using the electronic submission system used for manuscripts. Potential reviewers are queried in advance about their availability. While reviewers are asked to complete their reviews within 3 weeks of receiving the manuscript, more expeditious turnaround is highly valued. If you would like to be a peer reviewer, please send your CV to .

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Peer review is essential to a medical journal, and each year, those peer reviewers who have carried the heaviest load and reviewed the greatest number of manuscripts are recognized as members of the Journal’s Circle of Honor.

The Circle of Honor is the Journal’s acknowledgment of the indispensable contribution—the dedication, scholarship, and scientific rigor—generously donated by these individuals.

2006 Circle of Honor

James Dalen, M.D., M.P.H.

James H. Kocsis, M.D.

David C. Emelity, M.D.

Francisco A. Moreno, M.D.

Maurizio Fava, M.D.

Michael K. Popkin, M.D.

Marlene P. Freeman, M.D.

George M. Simpson, M.D.

Scott A. Freeman, M.D.

Michael E. Thase, M.D.

Anne Herring, R.N., Ph.D.

Mauricio F. Tohen, M.D., Dr.P.H.

David B. Herzog, M.D.

Jan Volavka, M.D., Ph.D.

James W. Jefferson, M.D.

Carlos A. Zarate, Jr., M.D.

John M. Kane, M.D.

Mark Zimmerman, M.D.

Samuel J. Keith, M.D.

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