Key Takeaways

  1. Cannabis exposure was common at admission: 43% were current users, 67% of current cannabis users used daily, and 13% of the full sample had multiple substance use, supporting routine substance-use assessment in psychiatric inpatient care for young adults with bipolar disorder and psychotic disorders.
  2. Cannabis use alone did not clearly predict rehospitalization across the full year after discharge after adjustment for covariates (HR=1.6; 95% CI, 1.0–2.5), so clinicians should interpret cannabis use as part of a broader early-risk profile rather than as a sustained 12-month predictor by itself.
  3. Family and illness-course factors carried independent risk: absent or conflicted family relationship was associated with readmission (HR =2.2; 95% CI, 1.4–3.2), and psychiatric hospitalization history was similarly associated (HR =2.1; 95% CI, 1.4–3.2).
  4. The observed readmission burden was substantial even outside cannabis status, with 95 of 187 patients readmitted within 1 year and a median delay of 95 days (interquartile range 1–3: 15; 349), which argues for follow-up planning well before the typical 3-month mark.
  5. Specialized addiction care appeared underused relative to need: 37% had a SUD diagnosis, but only 12% received specialized care for addiction, and among those readmitted within the first month, current specialized addiction treatment was 6.8% versus 12.8% in all others.
  6. Objective toxicology was infrequent despite high reported drug exposure, with toxic urinary screening performed for only 30% of patients; when young adults with bipolar disorder or psychotic disorders present with deterioration, selective toxicologic testing may help clarify substance-related contributors.
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