Original Research J Clin Psychiatry October 2026

From Hospital to Outpatient Care After Long-Acting Injectable Antipsychotic Initiation in Bipolar Disorder: Nationwide Evidence From Taiwan

JCP 2026;87(4):10.4088/JCP.26m16479

Full Article Read the complete peer-reviewed article in J Clin Psychiatry. JCP 2026;87(4):10.4088/JCP.26m16479 Clinical Summary Patients with bipolar disorder often relapse when daily medication adherence breaks down, leading to emergency visits, hospitalization, and disrupted continuity of care. This study asks a practical question clinicians face every day: after starting a second-generation long-acting injectable antipsychotic, does psychiatric care actually shift away from crisis services and toward planned outpatient follow-up? FAQ What did this study find after starting a second-generation long-acting injectable antipsychotic in bipolar disorder? 11 questions
Key Takeaways Only 500 of 2,919 bipolar disorder initiators met the study’s definition of stable use, underscoring that maintaining label-frequency-concordant long-acting injectable antipsychotic care over 12 months may be a major implementation challenge in routine practice. 6 takeaways Clinical Guide How should clinicians counsel and monitor patients with bipolar disorder after starting a second-generation long-acting injectable antipsychotic based on expected service-use changes? 5 steps