Key Takeaways

  1. This was a markedly impaired and comorbid adult ADHD sample: only 8% had no psychiatric comorbidity, while 53% had 4 or more psychiatric comorbidities, underscoring the need for broad diagnostic assessment when adults present with attention problems.
  2. Current ADHD symptoms were associated with substantial ongoing burden, with 22% reporting severe impairment and 50% reporting moderate impairment in the past month; functional severity should be assessed directly rather than inferred from symptom counts alone.
  3. Although men and women did not differ in total inattentive or hyperactive/impulsive symptom counts, their comorbidity patterns diverged: men had higher lifetime rates of conduct disorder and alcohol abuse, whereas women had higher rates of dysthymia, panic disorder, agoraphobia, simple phobia, and generalized anxiety disorder.
  4. Age did not meaningfully change adult ADHD symptom presentation in this cohort: when split at the median age of 38 years, there were no differences in the total number or type of endorsed inattentive and hyperactive/impulsive symptoms.
  5. The predominance of inattentive presentations was broad rather than limited to a single subtype, as 93% of adults with ADHD had either the predominately inattentive or combined subtypes; clinicians should ask specifically about distractibility, sustained attention, and sustained mental effort in adult evaluations.
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