Original Research J Clin Psychiatry July 2026

Mind and Metabolism in Crisis: US Mortality Involving Obesity and Psychiatric Disorders—Trends, Disparities, and ARIMA Projections

Full Article Read the complete peer-reviewed article in J Clin Psychiatry. Clinical Summary Patients with psychiatric illness and obesity face overlapping metabolic, behavioral, and treatment-related risks, yet national mortality patterns for this combination have been poorly defined. This analysis shows a steep long-term rise in US deaths involving both conditions, with clear disparities by sex, age, ethnicity, and geography that matter for whom psychiatrists screen, monitor, and prioritize for integrated care. FAQ How much did US mortality involving both obesity and psychiatric disorders increase between 1999 and 2023? 11 questions
Key Takeaways The sharpest acceleration after the prepandemic period occurred from 2018 to 2021 (APC 20.64%, P<.05), followed by a reversal from 2021 to 2023 (APC −9.35%, P<.05), suggesting clinicians should not interpret the recent decline as sustained improvement given the projected rebound in mortality. 6 takeaways Clinical Guide How should clinicians identify which psychiatric patients warrant the most intensive integrated metabolic and obesity-focused care? 7 steps
Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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