JCP Weekly February 20, 2018

Original Research

Predictors of Relapse in Youth With Major Depressive Disorder

Youth who are at risk for relapse of MDD may benefit from treatment strategies aimed at preventing the return of symptoms. This study looked at clinical characteristics associated with relapse during continuation treatment in depressed children and adolescents who had completed 3 months of treatment with fluoxetine or placebo. Read the article to see which characteristics predicted worse outcomes.

DOI: 10.4088/JCP.15m10330 | Posted: 02/20/2018

Original Research

Trajectory of Functional Connectivity in AD

People at risk of Alzheimer’s disease often have higher functional connectivity in several brain networks. Does this functional connectivity change over time—and is there a pattern of change specific to individuals susceptible to developing Alzheimer’s disease? Read this article to learn more.

DOI: 10.4088/JCP.17m11583 | Posted: 02/20/2018

Original Research

Economic Burden and Employment Status Change in Treatment-Resistant Depression

The economic burden of depression is well known. When patients do not respond to treatment, what effect does this resistance have on health costs and in the workplace? The authors of this article used a US commercial claims database to determine the independent effects of treatment resistance, including work absenteeism, relative to those of depression alone.

DOI: 10.4088/JCP.17m11725 | Posted: 02/20/2018

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