Case Report

PCC
Polydipsia-Related Hyponatremia in Autism
Case Report

April 30, 2026

The authors present the case of a 10-year-old boy with autism who presented to the ED with hyponatremia-related seizures due to compulsive water drinking.
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PCC
Diphenhydramine and Dextromethorphan Overdose
Case Report

April 28, 2026

The authors describe a case of intentional overdose with diphenhydramine and extended-release dextromethorphan-guaifenesin that initially presented with anticholinergic toxicity and later evolved into serotonin toxicity.
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PCC
Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome
Case Report

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.
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PCC
Osmotic Demyelination Syndrome Presenting as EPS
Case Report

April 21, 2026

A 44-year-old woman was initially referred for presumed domperidone-induced extrapyramidal symptoms, but further workup uncovered a complex interplay of hyponatremia, demyelination, and neuroleptic hypersensitivity.
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PCC
Cultural Manifestations of Bereavement in a Chinese American Patient
Case Report

April 16, 2026

The authors highlight the difficulties of applying western psychiatric concepts to cultural minorities, as seen in a case of complicated bereavement in a 54-year-old Chinese American woman.
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PCC
7-OH-Mitragynine–Induced Psychosis
Case Report

April 14, 2026

The authors present the case of a patient who developed psychosis and delirium following several months of heavy 7-OH use that persisted for nearly a week following cessation.
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PCC
Acitretin, Homocysteine, and Neuropsychiatric Symptoms
Case Report

April 14, 2026

This report describes a case of acitretin-associated hyperhomocysteinemia that induced neuropsychiatric symptoms in a patient with chronic plaque psoriasis, highlighting the need for monitoring.
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PCC
Dose-Dependent Valproic Acid–Induced Hyperkalemia
Case Report

April 9, 2026

The authors present the case of a young man with bradycardia and Jacobs syndrome, in which a clear, dose-dependent relationship between valproic acid and hyperkalemia was observed.
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PCC
Succinylcholine Misuse in a Health Care Worker
Case Report

April 7, 2026

A health care worker with a history of PTSD and substance use misused succinylcholine for stress relief and sleep, highlighting the risks of occupational access to high-risk medications among...
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PCC
Managing FND and Psychiatric Illness
Case Report

April 7, 2026

This case of a 54-year-old woman with schizoaffective disorder illustrates how stigma around psychiatric conditions can impact patient disposition, particularly in patient populations with complex neurological disorders.
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PCC
Bupropion-Dextromethorphan for Clinically Challenging Apathy
Case Report

April 2, 2026

This case shows potential benefits of glutamate system–activating medication in addressing clinically challenging apathy in a 44-year-old man with depression.
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PCC
A Unique Manifestation of Postpartum OCD
Case Report

March 31, 2026

This report explores the case of a woman with postpartum OCD, who exhibited a unique compulsion of taking excessive photos and videos of her surroundings.
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PCC
Mesial Temporal Sclerosis and Juvenile Myoclonic Epilepsy
Case Report

March 26, 2026

The authors present a rare case of coexisting right mesial temporal sclerosis and juvenile myoclonic epilepsy, underscoring the challenges in dual epilepsy syndromes and the importance of individualized, multidisciplinary...
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PCC
Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease
Case Report

March 24, 2026

This case highlights a rare but clinically significant dilemma: balancing essential corticosteroid replacement against neuropsychiatric toxicity.
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PCC
Mania and Cerebral Amyloid Angiopathy
Case Report

March 19, 2026

This report details a case in which a patient presented with mania in the setting of cerebral amyloid angiopathy and hypertension that did not abate until treatment with antihypertensives.
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PCC
Atypical Presentation of Autoimmune Encephalitis
Case Report

March 19, 2026

A 23-year-old woman presented with probable antibody-negative autoimmune encephalitis that initially mimicked a primary psychiatric disorder.
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PCC
Tacrolimus-Induced Parasomnia Posttransplantation
Case Report

March 17, 2026

The authors present a rare case of tacrolimus-induced parasomnia, adding to the body of evidence on its neurotoxic potential.
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PCC
Clozapine-Induced Antiphospholipid Syndrome
Case Report

March 12, 2026

A 68-year-old man with no pre‐existing risk factors experienced clozapine-induced antiphospholipid syndrome and a deep vein thrombosis.
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PCC
Caffeine for ICI Encephalitis
Case Report

March 5, 2026

With the increased use of immune checkpoint inhibitors, the potential for aseptic encephalitis poses a unique challenge to patient rehabilitation.
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PCC
Misophonia With Psychiatric Comorbidities
Case Report

March 3, 2026

This case highlights the need for enhanced recognition of misophonia, integrated care pathways, and improved mental health infrastructure in low- and middle-income countries.
PCC
Intranasal Tapentadol Dependence
Case Report

February 26, 2026

The authors present 2 cases of intranasal tapentadol dependence marked by rapid tolerance and significant physical and psychological issues.
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JCP
Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
Case Report

February 23, 2026

Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
PCC
Calcineurin Inhibitor–Induced Psychosis
Case Report

February 17, 2026

The authors report a case of delayed and recurrent calcineurin inhibitor–induced psychosis with both tacrolimus and cyclosporine, highlighting the need to better understand host vulnerability and risk stratification.
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PCC
Arm EMG and Detection of REM Sleep Without Atonia
Case Report

February 17, 2026

This case highlights the importance of utilizing arm EMG to accurately detect REM sleep without atonia, as REM sleep behavior disorder often precedes the development of α-synucleinopathies, such as...
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