Case Report

PCC
Psychiatric Symptoms After Stopping a GLP-1 Agonist
Case Report

Psychiatric Symptoms After Stopping a GLP-1 Agonist

October 22, 2026

This report describes 2 cases of mood and psychotic symptoms associated with discontinuation of GLP-1 agonists.
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PCC
Rope-Tying Behavior in Late-Life GAD
Case Report

Rope-Tying Behavior in Late-Life GAD

October 22, 2026

This case demonstrates an unusual manifestation of late-life anxiety in which voluntary physical restraint functioned as a maladaptive coping strategy during episodes of overwhelming autonomic and emotional arousal.
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PCC
Unexpected Butorphanol Dependence
Case Report

Unexpected Butorphanol Dependence

October 20, 2026

Initiation of butorphanol for acute pain increases the risk of iatrogenic dependence in patients with no history of psychoactive substance use.
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PCC
Methaqualone Ingestion in an Adolescent
Case Report

Methaqualone Ingestion in an Adolescent

October 15, 2026

An adolescent ingests what he believes to be an over-the-counter cold preparation obtained at an estate sale with the intent to “get a high.”
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PCC
Psychosis and Delirium During Menstruation
Case Report

Psychosis and Delirium During Menstruation

October 15, 2026

The authors report a case of recurrent delirium and psychosis temporally associated with co-occurring urinary tract infection and menstruation in a premenopausal woman.
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PCC
Use of ECT and Ketamine in a POLG-Related Disorder
Case Report

Use of ECT and Ketamine in a POLG-Related Disorder

October 13, 2026

Ketamine therapy and ECT are 2 treatment modalities that may be considered in patients with a POLG-related disorder and mood symptoms.
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PCC
Untreated Anorexia: A 40-Year Case
Case Report

Untreated Anorexia: A 40-Year Case

October 13, 2026

The authors present the case of a patient with a nontreated anorexia nervosa for more than 40 years, who developed severe medical complications secondary to the untreated psychiatric illness.
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PCC
Body Integrity Dysphoria and Online Identity Communities
Case Report

Body Integrity Dysphoria and Online Identity Communities

October 8, 2026

A transgender young adult was admitted to the hospital after intentionally submerging both feet in dry ice, resulting in severe frostbite and requiring bilateral below-knee amputations.
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PCC
Structured Serious Illness Communication
Case Report

Structured Serious Illness Communication

October 6, 2026

This case illustrates how early collaboration with an inpatient palliative care interdisciplinary team can promote patient-centered, goal-concordant care in the acute hospital setting.
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PCC
AI-Associated Psychosis
Case Report

AI-Associated Psychosis

October 1, 2026

The authors present the case of a 27-year-old woman with psychosis, in whom the use of generative AI colored her clinical presentation.
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PCC
Psychotherapy Based on a Buddhist Concept
Case Report

Psychotherapy Based on a Buddhist Concept

October 1, 2026

The author describes a perplexing case of a 14-year-old girl with autism and the use of a psychotherapeutic treatment intervention based on a Buddhist concept.
JCP
Worsening of Depression and Anxiety with Psilocybin
Case Report

Worsening of Depression and Anxiety with Psilocybin

September 30, 2026

A patient with undiagnosed cyclothymia, with a decade of depression, anxiety, and inattention, had severe worsening of depression and anxiety after a high-dose, lay-administered psilocybin session.
PCC
Atypical Depression and OSA Screening
Case Report

Atypical Depression and OSA Screening

September 29, 2026

Young patients with atypical depression, marked weight gain, and snoring can go years without formal obstructive sleep apnea screening, contributing to underdiagnosis within psychiatric care.
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PCC
Kratom-Induced Serotonin Syndrome
Case Report

Kratom-Induced Serotonin Syndrome

September 24, 2026

A 38-year-old man on a stable regimen of psychotropic medication developed serotonin syndrome after heavy kratom use.
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PCC
Esketamine For Depression in MS
Case Report

Esketamine For Depression in MS

September 22, 2026

This case of a 42-year-old man introduces intranasal esketamine as a potentially useful treatment option for depressive symptoms in a patient with multiple sclerosis.
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PCC
Olfactory Reference Syndrome Responding to Amisulpride
Case Report

Olfactory Reference Syndrome Responding to Amisulpride

September 17, 2026

The authors describe a case of olfactory reference syndrome in a 22-year-old woman, who presented with prominent referential beliefs and poor insight, closely resembling a first-episode psychosis.
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PCC
Lorazepam in Chronic Catatonia Reversal
Case Report

Lorazepam in Chronic Catatonia Reversal

September 10, 2026

This report describes chronic organic catatonia following cerebral malaria in a 17-year-old male, who experienced a marked response to lorazepam.
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PCC
When Obsession and Psychosis Become Indistinguishable
Case Report

When Obsession and Psychosis Become Indistinguishable

September 8, 2026

Differentiating obsessions from delusions is essential for accurate diagnosis and management, as comorbid obsessive-compulsive symptoms in schizophrenia complicate treatment and may influence cognitive and affective outcomes.
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PCC
Managing 7-hydroxymitragynine Withdrawal
Case Report

Managing 7-hydroxymitragynine Withdrawal

August 27, 2026

A 49-year-old man taking “7-OH” experienced significant opioid withdrawal symptoms that resolved with high-dose buprenorphine-naloxone treatment.
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PCC
Aripiprazole-Induced Hiccups
Case Report

Aripiprazole-Induced Hiccups

August 25, 2026

A 29-year-old man hospitalized for psychotic symptoms in the context of methamphetamine experienced persistent hiccups after starting aripiprazole.
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PCC
Renal Agenesis, Dysmorphism, and Schizophrenia
Case Report

Renal Agenesis, Dysmorphism, and Schizophrenia

August 18, 2026

The authors report a case of treatment-resistant schizophrenia with unilateral renal agenesis and minor physical anomalies, highlighting this rare association as well as treatment implications.
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PCC
Unexpected Improvement in Obsessive-Compulsive Disorder Symptoms Following Initiation of Bupropion
Case Report

Unexpected Improvement in Obsessive-Compulsive Disorder Symptoms Following Initiation of Bupropion

August 18, 2026

A 23-year-old woman with OCD and comorbid depression experienced an unexpected improvement in OCD symptoms following initiation of bupropion.
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PCC
Peduncular Hallucinosis With Right Thalamic Cavernous Angioma
Case Report

Peduncular Hallucinosis With Right Thalamic Cavernous Angioma

August 18, 2026

A 56-year-old woman developed visual and auditory hallucinations, delusions of jealousy and possession, and cognitive impairment associated with a thalamic lesion
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PCC
Volitional Mutism in Adulthood
Case Report

Volitional Mutism in Adulthood

August 6, 2026

The authors present a case of volitional mutism in a 42-year-old woman and highlight the differential diagnosis.
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