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Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
The Role of Chronic Anhedonia in the Relationship Between Treatment-Resistant Depression and Suicidality
Original Research

The Role of Chronic Anhedonia in the Relationship Between Treatment-Resistant Depression and Suicidality

September 21, 2026

Chronic anhedonia is significantly associated with an increased risk of suicidal ideation and attempts in patients with treatment-resistant depression.
, , , et al
JCP
Correction

Correction. Evaluation of Sexual Function With Adjunctive Lumateperone in Patients With Major Depressive Disorder

September 17, 2026

JCP
Paliperidone Palmitate 351 mg as Alternative Maintenance Doses in Patients With Schizophrenia or Schizoaffective Disorder
Insights ▶ Video

Paliperidone Palmitate 351 mg as Alternative Maintenance Doses in Patients With Schizophrenia or Schizoaffective Disorder

September 16, 2026

This analysis suggests that maintenance doses of paliperidone palmitate 351 mg at different dosing intervals may offer additional treatment options for clinical use.
, , , et al
JCP
Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress
Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress

September 14, 2026

Adjunctive lumateperone 42 mg significantly improved depression and anxiety symptoms in patients with MDD with inadequate antidepressant response and anxious distress
, , , et al
JCP
Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET
Original Research

Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET

September 14, 2026

Data from the EPINET project reveal wide variation in the prescription of LAIs and clozapine across first-episode specialty care clinics.
, , , et al
JCP
Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages
Original Research

Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages

September 9, 2026

The prevalence of probable perinatal depression was comparable to that in US women, demonstrating the app’s ability to identify perinatal depression.
, , , et al
JCP
Using Speech to Predict MDD and GAD During Pregnancy
Original Research

Using Speech to Predict MDD and GAD During Pregnancy

September 9, 2026

Influential speech features for prediction of MDD and GAD during pregnancy were similar to those in the general population.
, , , et al
JCP
The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD
Podcast

The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD

September 8, 2026

Benjamin Brody, MD, discusses ketamine’s REMS-regulated future, esketamine safety, dysphoric dissociation, and what psilocybin approval means for psychiatry.
,
JCP
Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder
Original Research

Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder

September 2, 2026

Adjunctive lumateperone 42 mg did not worsen sexual functioning and was not associated with treatment-related sexual dysfunction.
, , , et al
JCP
Electroconvulsive Therapy and All-Cause, Nonsuicide, and Suicide Mortality
Clinical and Practical Psychopharmacology

Electroconvulsive Therapy and All-Cause, Nonsuicide, and Suicide Mortality

August 31, 2026

Evidence on the association of ECT with lower risk of short- and long-term all-cause mortality, nonsuicide mortality, and suicide mortality is reviewed.
JCP
Obstetric Risk Associated with Stimulant vs Nonstimulant Treatment
Original Research

Obstetric Risk Associated with Stimulant vs Nonstimulant Treatment

August 26, 2026

Stimulant and nonstimulant use during pregnancy were both associated with increased risk for obstetric complications vs no medication.
,
JCP
The Prescriber’s Guide to Oral Ketamine for Depression
Clinical and Practical Psychopharmacology

The Prescriber’s Guide to Oral Ketamine for Depression

August 26, 2026

Explains clinical contexts in which oral ketamine can be used and presents a detailed protocol for the use of this intervention.

Insightful. Evidence-based. Human-centered.

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Psychiatrist Steven Berkowitz, MD, discusses psychedelic medicine for trauma treatment

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