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Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Association of Immediate Postpartum Anxiety With Postpartum Depression
Original Research

October 15, 2025

The prevalence of immediate postpartum anxiety (IPPA) in this population was 24%, and 7.4% for severe anxiety. Among women with IPPA, 31.2% developed postpartum depression.
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JCP
Brexpiprazole for the Treatment of Co-Occurring Schizophrenia and Substance Use Disorder
Original Research

October 13, 2025

This pilot trial suggests that brexpiprazole might be beneficial in reducing substance craving and use and improve quality of life in this difficult-to-treat patient population.
, , , et al
JCP
Treatment with (Es)ketamine in Catatonia: A Systematic Review of Case Reports
Brief Report

October 13, 2025

Recent evidence suggests that NMDA receptor antagonists, such as ketamine, may offer benefit in catatonia. This systematic review was conducted to evaluate the efficacy and safety of ketamine and…
, , , et al
JCP
Depression at 2 Months Postpartum: Results from the French National Perinatal Survey
Original Research

October 8, 2025

The prevalence of postpartum depression (PPD) at 2 months was 16.7%. Factors associated with PPD included age ≤29 or ≥40 years, lower levels of health literacy, and a history…
, , , et al
JCP
Dosing Patients With Oral Iron Supplements: Practical Guidance
Clinical and Practical Psychopharmacology

October 8, 2025

The relevance of iron in neuropsychiatry is discussed, with guidance on how to dose oral iron supplements so as to maximize its absorption.
JCP
Esmethadone (REL-1017) in Patients with Major Depressive Disorder and Antidepressant Tachyphylaxis
Original Research

October 6, 2025

Esmethadone may be a potentially safe and effective adjunctive treatment for patients with MDD and antidepressant tachyphylaxis.
, , , et al
JCP
Symptom Network Analysis of ADHD and Emotional Symptoms in Adults
Original Research

October 1, 2025

Emotional dysregulation symptoms play a significant role in connecting the core ADHD symptoms, particularly those related to the inattention dimension.
, , , et al
JCP
Emory Treatment Resistance Interview for PTSD—Short Version
Original Research

October 1, 2025

The E-TRIP-S offers a simplified method for assessing treatment resistance among PTSD patients.
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JCP
Effects of Interpersonal and Social Rhythm Therapy on Suicidal Ideation in Adults with Bipolar II Depression
Original Research

September 29, 2025

There was no significant difference in suicidal ideation in those receiving IPSRT plus placebo vs IPSRT plus quetiapine. IPSRT has the potential to mitigate suicidal ideation in patients with…
, , , et al
JCP
PSI Response: FDA Panel Discussion Regarding SSRIs in Pregnancy

September 24, 2025

A response from Postpartum Support International expressing concern about the July 2025 FDA panel discussion on SSRIs in pregnancy.
JCP
Aripiprazole or Bupropion Augmentation vs Switching to Bupropion in Treatment Resistant Depression
Original Research

September 22, 2025

In this model, augmentation with bupropion better balanced efficacy and tolerability in TRD in adults under 85 than did switching to bupropion or augmentation with aripiprazole. Augmentation with aripiprazole…
, , , et al
JCP
Analytical Review of Depression and Suicidality from Finasteride
Narrative Review

September 22, 2025

This review looks at the potential for finasteride to cause depression and suicidality and makes policy recommendations for regulating and monitoring drug safety.

Expert Consensus on Aripiprazole LAIs in Clinical Practice

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Figure. Image of a syringe on two vials highlights aripiprazole monohydrate LAI clinical use in Bipolar I Disorder.

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