JCP Weekly December 4, 2018

Original Research

Sudden Improvement in Symptoms During Antidepressant Clinical Trials

If a patient’s depressive symptoms subside very quickly after antidepressant treatment is initiated, do those gains represent a true and lasting response? This study examined whether sudden improvement in individuals with late-life depression predicted longer-term positive response at endpoint.

DOI: 10.4088/JCP.18m12353 | Posted: 12/04/2018

Original Research

Placebo Effects in LAI Trials for Schizophrenia

Poor treatment adherence masks the true extent of placebo effects in trials of antipsychotics in schizophrenia. Can use of an injectable placebo in double-blind trials of long-acting injectable antipsychotics circumvent issues of adherence and provide a clearer picture of placebo effects? Read this article to find out.

DOI: 10.4088/JCP.18m12144 | Posted: 12/04/2018

ASCP Corner

Inaccurate Prescribing Warnings in EMR Systems: A Survey

Are electronic prescribing alerts useful or simply annoying? A survey gathered the opinions of ASCP members on several aspects of these alerts, including how often they are inaccurate and how the clinician tended to proceed when presented with one. The authors also reflect on what these findings may mean.

DOI: 10.4088/JCP.18ac12536 | Posted: 12/04/2018

Original Research

Adjunctive Anti-Inflammatory Treatments for Bipolar Depression

Nonsteroidal anti-inflammatory drugs (NSAIDs) and antioxidative treatments have shown antidepressant potential as adjunct treatments. Read this article to learn if adjunctive treatment with the antioxidative agent N-acetylcysteine, the NSAID aspirin, or both helped reduce depressive symptoms in patients with bipolar depression.

DOI: 10.4088/JCP.18m12200 | Posted: 12/04/2018

See past JCP Weekly