Gabapentin Augmentation for Fluoxetine-Treated Patients With Obsessive-Compulsive Disorder

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Sir: Serotonin reuptake inhibitors (SRIs) are the most effective pharmacologic treatment for obsessive-compulsive disorder (OCD). However, few patients have a complete response to SRIs. Because augmentation strategies are needed, we initiated a pilot study of gabapentin in patients with OCD who had a partial or incomplete response to SRI treatment.

J Clin Psychiatry 1998;59(9):480-481