New-Onset Diabetes Mellitus Associated With the Initiation of Quetiapine Treatment

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Letter to the Editor

Sir: Quetiapine is a novel antipsychotic that antagonizes both serotonergic (5-HT1A and 5-HT2) and dopaminergic (D1 and D2) receptors. The manufacturer describes hypoglycemia, hyperglycemia, and diabetes mellitus as infrequent side effects (0.1%–1.0%). The following is a case report of possible quetiapine- induced onset of diabetes mellitus.

J Clin Psychiatry 1999;60(8):556-557