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Paroxetine-Induced Angioedema and Tongue Swelling

J Clin Psychiatry 1996;57(10):487 [letter]

Letter to the Editor

Sir: Serotonin selective reuptake inhibitors (SSRIs) are relatively new antidepressant medications that are rapidly gaining in popularity because they have fewer and less severe adverse effects than “older” antidepressants (e.g., amitriptyline). However, the increased use of SSRIs also allows their adverse effect profile to be more completely described. We feel clinicians should be aware of a possible association of SSRIs and angioedema.