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Validation for the Tardive Dyskinesia Impact Scale, a Patient-Reported Outcome Measure in Valbenazine Clinical Trials
Narrative Review

April 29, 2026

The TDIS followed a similar trajectory to other clinician- and patient-reported outcomes measured in tardive dyskinesia clinical trials, and a change of 4 points in total score is considered…
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JCP
The Patient Perspective on Tardive Dyskinesia
Commentary

April 29, 2026

Patients’ perspectives on their experiences with tardive dyskinesia provide critical insights that go beyond the information provided by clinical assessments.
PCC
Diphenhydramine and Dextromethorphan Overdose
Case Report

April 28, 2026

The authors describe a case of intentional overdose with diphenhydramine and extended-release dextromethorphan-guaifenesin that initially presented with anticholinergic toxicity and later evolved into serotonin toxicity.
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PCC
Catatonia, Neurocognitive Disorders, and End-of-Life Care
Letter to the Editor

April 28, 2026

The authors present a combined cohort of 4 patients with baseline neurocognitive disorders who developed catatonia shortly before death.
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JCP
SSRI, SNRI, or Other Antidepressant Use Not Associated With Differential Outcomes in Ketamine or Esketamine Treatment
Brief Report

April 27, 2026

No group differences were seen between concurrent oral antidepressant class and clinical outcomes in patients treated with IV ketamine or IN esketamine.
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PCC
Antidepressant Monitoring Referrals to Higher-Level Services
Original Research

April 23, 2026

This study examined predictors of referral from a collaborative care model antidepressant monitoring program to higher levels of psychiatric services.
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Original Research

PCC
Alcohol Craving and Mood Disorders
Original Research

April 21, 2026

Craving and alcohol-related severity differ between major depressive disorder and bipolar disorder even during euthymia, so accurate diagnosis is crucial.
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JCP
Phase 2b Study to Evaluate Basmisanil as Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia
Original Research

April 15, 2026

Although basmisanil did not improve cognitive deficits, the results offer insight into factors that should facilitate design of more informative trials.
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JCP
Suicide Risk and VHA Utilization Among Those with a Suicide Attempt in the US Military
Original Research

April 13, 2026

Veterans with a history of suicide attempt prior to transitioning out of military service were more likely to have a suicide attempt or die from suicide after separation than…
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The Journal of Clinical Psychiatry

The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals. Now featuring The JCP Podcast: conversations with experts exploring the research shaping clinical care.  

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The Emerging Role of GLP-1s in Psychiatry with Roger S. McIntyre, MD, FRCPC
Podcast

April 21, 2026

GLP-1 receptor agonists in psychiatric care: Dr. Roger McIntyre reviews their neuroscience, clinical applications, safety considerations, and future potential.
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JCP
Catatonia as a Case Study in Psychiatric Decision-Making
ASCP Corner

April 20, 2026

Historical approaches to clinical decision-making are discussed, followed by a decision-making matrix that incorporates expected risks and treatment benefits into management decisions.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome
Case Report

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.
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PCC
Osmotic Demyelination Syndrome Presenting as EPS
Case Report

April 21, 2026

A 44-year-old woman was initially referred for presumed domperidone-induced extrapyramidal symptoms, but further workup uncovered a complex interplay of hyponatremia, demyelination, and neuroleptic hypersensitivity.
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