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Neuropsychiatric Symptom Clusters and Brain Structure in Alzheimer’s Disease
Original Research

March 16, 2026

Neuropsychiatric symptoms in Alzheimer’s disease separate into hyperactivity, psychosis, neurovegetative, and affective clusters, supporting a cluster-based paradigm linking behavioral symptoms with brain structure and functional decline.
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JCP
Neural Dysconnectivity and Affective Disorders: Integrating Sleep and Emotional Regulation Perspectives
Letter to the Editor

March 16, 2026

The authors discuss sleep disturbance in the context of recent research on functional dysconnectivity in the brain’s triple networks.
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JCP
Triple Network Dysconnectivity and Sleep Disturbance in Young People With Suicidal Ideation: Reply to Ferruzzi et al
Letter to the Editor

March 16, 2026

Cheng et al reply to a letter regarding their recent study of triple network functional dysconnectivity in major affective disorders.
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PCC
Clozapine-Induced Antiphospholipid Syndrome
Case Report

March 12, 2026

A 68-year-old man with no pre‐existing risk factors experienced clozapine-induced antiphospholipid syndrome and a deep vein thrombosis.
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PCC
Role of tDCS in Autism
Meta-Analysis

March 12, 2026

Transcranial direct current stimulation improves core autism spectrum disorder symptoms, particularly social responsiveness and behavioral regulation, with stimulation of the dorsolateral prefrontal cortex showing the greatest benefit.
, , , et al
JCP
Life After Clozapine: Managing Treatment-Resistant Schizophrenia When Clozapine Is No Longer an Option
ASCP Corner

March 11, 2026

The authors discuss treatment options and reinitiation of clozapine following clozapine discontinuation.
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Original Research

JCP
Temporal Dynamics of Antidepressant Response Following Brexanolone Treatment in Postpartum Depression
Original Research

March 11, 2026

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PCC
Ultra–Low-Dose Mirtazapine for Chronic Insomnia
Original Research

March 10, 2026

In patients with insomnia disorder, a clinically relevant effect was seen with low-dose mirtazapine (3.75 mg) on insomnia severity from 1–3 months.
, , , et al
JCP
Safety and Efficacy of Maintenance Treatment with Aripiprazole Once-Monthly in Black/African American Adults With Bipolar I Disorder
Original Research

March 9, 2026

The safety and efficacy of AOM 400 were comparable between Black/African American and non-Black/African American patients with bipolar I disorder
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The Journal of Clinical Psychiatry

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Behind the Manuscript: Inpatient Treatment of Suicidality with Brett Jones, MD, MSc, PhD, FRCPC
Podcast

March 10, 2026

Dr. Brett Jones reviews evidence-based interventions for inpatient suicidality: ketamine, chronotherapy, and dialectical behavior therapy for acute psychiatric care.
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JCP
Efficacy of Olanzapine/Samidorphan on Negative Symptoms
Original Research

March 9, 2026

Olanzapine/samidorphan was associated with significant and durable improvement in negative symptoms of schizophrenia, overall and among patients with prominent and predominant negative symptoms.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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Psychosis and Kratom
Letter to the Editor

March 10, 2026

The authors discuss the possible association between psychosis and kratom use.
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PCC
Administering ECT to Critically Ill Patients
Rounds in the General Hospital

March 5, 2026

ECT can be lifesaving for critically ill individuals with severe psychiatric and neuropsychiatric conditions; however, cardiac monitoring is essential.
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Consensus Report on XT Use in Practice

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