Reply to Letter to the Editor "Efficacy of 17β-Estradiol on Depression: Is Estrogen Deficiency Really Necessary?"

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Letter to the Editor

Sir: We are grateful to Dr. Soares and colleagues for their comments on postpartum depression and our finding of positive treatment effect with natural 17β-estradiol (E2)1 and for reporting their similar observation in perimenopausal women.

J Clin Psychiatry 2002;63(5):451-452 [letter]