Efficacy of Continuation Treatment With Hypericum perforatum in Depression

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Letter to the Editor

Sir: Several studies have suggested that Hypericum perforatum (St. John’s wort) is efficacious for the treatment of mild-to-moderate depression. Most of these studies involved short-term treatment of an acute depressive episode. There are no extensive data from studies on whether Hypericum is an efficacious maintenance treatment for depression.

J Clin Psychiatry 2002;63(5):455 [letter]