Meta-Analysis

JCP
Treatment of PTSD in Patients With Severe Mental Illness
Meta-Analysis

Treatment of PTSD in Patients With Severe Mental Illness

May 25, 2021

For patients who have PTSD and also have a severe mental illness, can psychotherapies for PTSD still be effective? If so, what component might offer greater efficacy?
, , , et al
JCP
Meta-Analysis

Omega-3 Fatty Acids for Borderline Personality Disorder

May 4, 2021

This comprehensive meta-analysis informs clinicians and patients about the potential effectiveness of omega-3 fatty acids as add-on therapy for borderline personality disorder.
, ,
JCP
Meta-Analysis

Single vs Multiple Dose Regimens of Psychotropic Drugs

February 23, 2021

Single-daily-dose regimens are easier for patients to follow than multiple-dose regimens and may increase adherence. But do they work as well? And are they safe? Read this meta-analysis to...
, , , et al
JCP
Meta-Analysis

OCD Prevalence and Gender

June 23, 2020

Women seem more likely than men to develop obsessive-compulsive disorder (OCD), but findings of individual studies are inconsistent. This meta-analysis estimated the worldwide prevalence of OCD to determine if...
, ,
JCP
Meta-Analysis

Antidepressants and Pregnancy

June 9, 2020

Read a systematic review examining how antidepressant discontinuation affects the risk of depression relapse during pregnancy.
, , , et al
JCP
Meta-Analysis

Pharmacologic Treatment of Tardive Dyskinesia

May 26, 2020

Many augmentation agents have been examined regarding efficacy for antipsychotic-induced tardive dyskinesia (TD).The goal of this systematic review and meta-analysis was to examine the efficacy of these agents used...
, , , et al
JCP
Meta-Analysis

Deep Brain Stimulation in Refractory OCD

May 26, 2020

First-line treatments for OCD include selective serotonin reuptake inhibitors and cognitive-behavioral therapy. But what do you do when patients do not respond to these or second-line strategies? In this...
, ,
JCP
Meta-Analysis

Esketamine Augmentation in Major Depressive Disorder

May 26, 2020

The FDA has now approved intranasal esketamine as augmention in treatment-resistant depression, and recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an...
, , , et al
JCP
Meta-Analysis

Interventions and Transition in Youth at Risk of Psychosis

May 19, 2020

The most effective treatment for reducing transition to psychosis among youth at clinical high risk for psychosis has not been determined. The present systematic review and meta-analyses summarize all...
, , , et al
JCP
Meta-Analysis

Medication Discontinuation and Quality of Life in ADHD

March 24, 2020

For ADHD patients who responded to medication treatments, does discontinuing those medications affect quality of life more adversely than continuing them? This study compares the effects of continuing versus...
, , , et al
JCP
Meta-Analysis

Long-Term Outcomes of Postpartum Psychosis

March 10, 2020

Some women experience severe affective episodes outside the postpartum period after an initial episode of postpartum psychosis, though others do not. This meta-analysis estimates the risk of recurrence after...
, , , et al
JCP
Meta-Analysis

Varenicline for Alcohol Use Disorders

February 25, 2020

Varenicline reduces smoking. Since alcohol use and tobacco use disorders are often comorbid, does the effectiveness of varenicline in reducing tobacco use translate to a similar effectiveness for alcohol-related...
, , , et al
JCP
Meta-Analysis

Exercise for Late-Life Depression

January 21, 2020

Evidence for an effect of exercise on depression in older adults is scant and heterogeneous. This meta-analysis included trials with a specific exercise dose and assessed sources of heterogeneity—read...
, , , et al
PCC
Meta-Analysis

Weight Gain in Severe Mental Illness

December 19, 2019

Patients with severe mental illness tend to have a higher prevalence of metabolic disorders. This review updates the current evidence on the effectiveness of add-on medications to treat weight...
, , , et al
PCC
Meta-Analysis

Gabapentin and Withdrawal in Alcohol Use Disorder

August 22, 2019

While benzodiazepines are considered the standard of care for alcohol withdrawal, gabapentin is a valuable alternative that can also help with cravings and abstinence long term. Read on to...
, , , et al
JCP
Meta-Analysis

Anxiety Disorders in Pregnant and Postpartum Women

July 23, 2019

Addressing anxiety disorders in pregnant women and new mothers is important, especially given the potential effects on offspring. Do you know which disorders are most common? Read this meta-analysis...
, , , et al
JCP
Meta-Analysis

Benzodiazepines and Congenital Malformations

July 9, 2019

Is prenatal benzodiazepine use associated with an increased risk of congenital malformations? What about concurrent use of a benzodiazepine and an antidepressant? Does the trimester have an effect? See...
, , , et al
JCP
Meta-Analysis

Sleep-Associated Adverse Events With ADHD Treatment

April 30, 2019

Methylphenidate is related to sleep-related adverse events. This meta-analysis sought to quantify this impact of methylphenidate and determine the varieties of sleep problems associated with this drug.
, , , et al
JCP
Meta-Analysis

Updated Meta-Analysis of Pediatric Bipolar Disorder Studies

April 2, 2019

The prevalence of pediatric bipolar disorder is an ongoing topic of debate, and the body of research has grown in recent years. Read this article to learn about current...
, ,
JCP
Meta-Analysis

Computer-Assisted CBT for Depression

March 19, 2019

Computer-assisted cognitive-behavior therapy (CCBT) allows clinicians to deliver evidence-based care to more patients than would be possible with standard CBT. This meta-analysis sought to determine if additional clinician support...
, , , et al
JCP
Meta-Analysis

Cannabinoids for Agitation and Aggression in AD

January 29, 2019

Given the limited efficacy and questionable safety profiles of current pharmacologic treatments of agitation in Alzheimer's disease (AD), the therapeutic potential of natural and synthetic cannabinoids are being explored...
, , , et al
JCP
Meta-Analysis

eHealth Interventions for Perinatal Anxiety

January 22, 2019

eHealth interventions are effective for the treatment of anxiety in the general population, though results of individual studies of perinatal anxiety have been mixed. Given the high prevalence of anxiety...
, ,
JCP
Meta-Analysis

Meta-Analysis of Clozapine for Tardive Dyskinesia

September 18, 2018

Tardive dyskinesia, a side effect of antipsychotics, is a persistent and disabling problem among patients with schizophrenia. Could a switch to clozapine help? This meta-analysis looks at 16 studies...
, , , et al
JCP
Meta-Analysis

Antenatal Anxiety and Adverse Perinatal Outcomes

September 4, 2018

Anxiety is common during pregnancy, but reviews to date of the impact of anxiety on perinatal outcomes have been narrow in focus. This systematic review and meta-analysis synthesizes available...
, , , et al

Learn More About Psychedelics in Psychiatry

Explore the Collection
Neural network illustration symbolizing psychedelic research advancements

Subscribe to read
more articles

Subscribe