Ian Mackey, MS, PA-C
Psychiatric Medicine Associates, LLC, Skokie, Illinois
			                Case Series
			
            
                
    Esketamine Augmented With Dextromethorphan/Bupropion for Treatment Resistant Depression: A Case Series
November 3, 2025
Three patients with TRD who had no or partial response to esketamine monotherapy as part of a clinical trial received augmentation with dextromethorphan/bupropion 45 mg/105 mg daily.