Grief, a natural response to loss, can sometimes evolve into complicated grief or major depression. Recognizing its manifestations and offering supportive care is crucial. The Journal of Clinical Psychiatry offers in-depth insights into the psychiatric aspects of grief, from normal grieving processes to pathological manifestations. Our expert editors curate content that is compassionate and evidence-based, ensuring psychiatrists can support individuals navigating the challenges of loss.
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Original Research
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
May 4, 2026
In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.