This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Articles

The Use of Selective Serotonin Reuptake Inhibitors in Treating Alcoholic Subtypes

Article Abstract

The usefulness of selective serotonin reuptake inhibitors (SSRIs) to treat alcohol dependencecontinues to be a subject of debate. Most recently, investigations have tried to predict whether agiven patient will respond to SSRIs in terms of reducing excessive alcohol drinking. The subtypingof alcohol-dependent individuals has ranged from relatively simple classifications (e.g., presence ofcomorbid depression) to more complex classifications (e.g., potential to have abnormalities in serotonin[5-HT] neurotransmission). Although only a few studies have been completed, results thus farindicate that alcoholic subgroups are differentially responsive to 5-HT pharmacotherapy with respectto drinking-related outcomes. In addition, there are preliminary results encouraging the use ofSSRIs in combination with other medications for treating alcohol dependence in patients with andwithout comorbid psychiatric disorders. Information from these studies is promising, suggesting theneed for further investigation.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 62

Quick Links: Addiction , Substance Use Disorders